ID   GP1D_CHLMU              Reviewed;         451 AA.
AC   Q46437;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Probable plasmid replicative DNA helicase;
DE            EC=3.6.4.12;
DE   AltName: Full=DnaB-like protein;
DE   AltName: Full=Virulence plasmid protein pGP1-D;
GN   OrderedLocusNames=TC_A03;
OS   Chlamydia muridarum (strain MoPn / Nigg).
OG   Plasmid pMoPn.
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=243161;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=MoPn / Nigg;
RX   PubMed=9202459; DOI=10.1099/00221287-143-6-1847;
RA   Thomas N.S., Lusher M., Storey C.C., Clarke I.N.;
RT   "Plasmid diversity in Chlamydia.";
RL   Microbiology 143:1847-1854(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MoPn / Nigg;
RX   PubMed=10684935; DOI=10.1093/nar/28.6.1397;
RA   Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O.,
RA   Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S.,
RA   Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J.,
RA   Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G.,
RA   Salzberg S.L., Eisen J.A., Fraser C.M.;
RT   "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae
RT   AR39.";
RL   Nucleic Acids Res. 28:1397-1406(2000).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC   -!- SIMILARITY: Belongs to the helicase family. DnaB subfamily.
CC       {ECO:0000305}.
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DR   EMBL; X78726; CAA55374.1; -; Genomic_DNA.
DR   EMBL; AE002162; AAF39713.1; -; Genomic_DNA.
DR   PIR; S44161; S44161.
DR   RefSeq; WP_010231984.1; NZ_ACOV01000005.1.
DR   AlphaFoldDB; Q46437; -.
DR   SMR; Q46437; -.
DR   STRING; 243161.TC_A03; -.
DR   EnsemblBacteria; AAF39713; AAF39713; TC_A03.
DR   GeneID; 1245519; -.
DR   KEGG; cmu:TC_A03; -.
DR   PATRIC; fig|243161.6.peg.3; -.
DR   eggNOG; COG0305; Bacteria.
DR   HOGENOM; CLU_005373_0_1_0; -.
DR   OMA; YPSIDEH; -.
DR   OrthoDB; 1709134at2; -.
DR   Proteomes; UP000000800; Plasmid pMoPn.
DR   GO; GO:1990077; C:primosome complex; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-KW.
DR   CDD; cd00984; DnaB_C; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR036185; DNA_heli_DnaB-like_N_sf.
DR   InterPro; IPR007694; DNA_helicase_DnaB-like_C.
DR   InterPro; IPR007693; DNA_helicase_DnaB-like_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00772; DnaB; 1.
DR   Pfam; PF03796; DnaB_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF48024; SSF48024; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51199; SF4_HELICASE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; DNA-binding; Helicase; Hydrolase;
KW   Nucleotide-binding; Plasmid; Primosome.
FT   CHAIN           1..451
FT                   /note="Probable plasmid replicative DNA helicase"
FT                   /id="PRO_0000102036"
FT   DOMAIN          194..451
FT                   /note="SF4 helicase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00596"
FT   BINDING         225..232
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00596"
SQ   SEQUENCE   451 AA;  51491 MW;  69AC93C0082F3EE2 CRC64;
     MKTNSEIENR MQDIEYALLG KALVFEDCTE YILRQLVNYE FKCSRHKNIF IVFKHLKDNA
     LPITVDSAWE ELLRRRVKDI DKSYLGIMLH DAMFNDKLRP ISHTVLLDDL SVCSAEENLT
     NFIFRSFNEY NENPLRRSPF LLLDRIKDRL DRTIAKTFST RSVRGRSVYD IFSQAELGVL
     ARIKKRRAAY SENNDSFYDG LPTGYQDIDS KGVILANGNF VIIAARPSIG KTALAIDIAI
     NIAIHQRRRV GFLSLEMSAG QIVERIISNL TGVSGEKLQR GSLSEEEIFC IEEAGNTIRD
     SHLYICSDNQ YKLNLIANQI RLLKRDDRVD VIFIDYLQLI NSSVGENRQN EIADISRTLR
     GLAAELNIPI VCLSQLSRKV EDRANKVPML SDLRDSGQIE QDADVILFIN RKETSPNCEI
     TVGKNRHGSV FSTVLQFDPK TSKFSAIKKV W