ID   GP28_BPT4               Reviewed;         177 AA.
AC   P13336; Q9T0T7;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   15-AUG-2003, sequence version 4.
DT   02-DEC-2020, entry version 86.
DE   RecName: Full=Baseplate hub assembly protein gp28;
DE   AltName: Full=Gene product 28;
DE            Short=gp28;
GN   Name=28;
OS   Enterobacteria phage T4 (Bacteriophage T4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
OX   NCBI_TaxID=10665;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7612935; DOI=10.3109/10425179509029364;
RA   Bova R., Cascino A., Cipollaro M., Gargano S., Grau O., Micheli M.R.,
RA   Santoro M., Scarlato V., Storlazzi A.;
RT   "Bacteriophage T4 gene 28.";
RL   DNA Seq. 5:199-201(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12626685; DOI=10.1128/mmbr.67.1.86-156.2003;
RA   Miller E.S., Kutter E., Mosig G., Arisaka F., Kunisawa T., Ruger W.;
RT   "Bacteriophage T4 genome.";
RL   Microbiol. Mol. Biol. Rev. 67:86-156(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 168-177.
RX   PubMed=3363870; DOI=10.1016/0042-6822(88)90622-8;
RA   Ishimoto L.K., Ishimoto K.S., Cascino A., Cipollaro M., Eiserling F.A.;
RT   "The structure of three bacteriophage T4 genes required for tail-tube
RT   assembly.";
RL   Virology 164:81-90(1988).
RN   [4]
RP   SUBUNIT.
RX   PubMed=2403438; DOI=10.1128/jvi.64.1.143-154.1990;
RA   Watts N.R., Coombs D.H.;
RT   "Structure of the bacteriophage T4 baseplate as determined by chemical
RT   cross-linking.";
RL   J. Virol. 64:143-154(1990).
RN   [5]
RP   FUNCTION, AND INTERACTION WITH GP27.
RX   PubMed=10756710;
RA   Nieradko J., Koszalka P.;
RT   "Evidence of interactions between Gp27 and Gp28 constituents of the central
RT   part of bacteriophage T4 baseplate.";
RL   Acta Microbiol. Pol. 48:233-242(1999).
RN   [6]
RP   REVIEW ON FUNCTION.
RX   PubMed=14625682; DOI=10.1007/s00018-003-3072-1;
RA   Leiman P.G., Kanamaru S., Mesyanzhinov V.V., Arisaka F., Rossmann M.G.;
RT   "Structure and morphogenesis of bacteriophage T4.";
RL   Cell. Mol. Life Sci. 60:2356-2370(2003).
RN   [7]
RP   REVIEW ON FUNCTION.
RX   PubMed=21129200; DOI=10.1186/1743-422x-7-355;
RA   Leiman P.G., Arisaka F., van Raaij M.J., Kostyuchenko V.A., Aksyuk A.A.,
RA   Kanamaru S., Rossmann M.G.;
RT   "Morphogenesis of the T4 tail and tail fibers.";
RL   Virol. J. 7:355-355(2010).
CC   -!- FUNCTION: Baseplate hub assembly chaperone involved in the tail
CC       assembly. {ECO:0000269|PubMed:10756710, ECO:0000303|PubMed:21129200}.
CC   -!- SUBUNIT: The gp27 and gp28 proteins seem to combine to form a small hub
CC       precursor during morphogenesis. {ECO:0000305|PubMed:10756710,
CC       ECO:0000305|PubMed:21129200, ECO:0000305|PubMed:2403438}.
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DR   EMBL; X56651; CAA39973.1; -; Genomic_DNA.
DR   EMBL; AF158101; AAD42436.2; -; Genomic_DNA.
DR   EMBL; M20298; AAA32537.2; -; Genomic_DNA.
DR   PIR; S25492; S25492.
DR   RefSeq; NP_049804.2; NC_000866.4.
DR   TCDB; 1.K.1.1.1; the gp27/5 t4-baseplate (t4-bp) family.
DR   GeneID; 1258697; -.
DR   KEGG; vg:1258697; -.
DR   Proteomes; UP000009087; Genome.
DR   GO; GO:0098003; P:viral tail assembly; IEA:UniProtKB-KW.
DR   InterPro; IPR024342; Phage_T4_Gp28.
DR   Pfam; PF11110; Phage_hub_GP28; 1.
PE   1: Evidence at protein level;
KW   Late protein; Reference proteome; Viral release from host cell;
KW   Viral tail assembly.
FT   CHAIN           1..177
FT                   /note="Baseplate hub assembly protein gp28"
FT                   /id="PRO_0000165016"
SQ   SEQUENCE   177 AA;  20123 MW;  76577648F4ED6892 CRC64;
     MNLNLILPLK KVVLPISNKE VSIPKMGLKH YNILKDVKGP DENLKLLIDS ICPNLSPAEV
     DFVSIHLLEF NGKIKSRKEI DGYTYDINDV YVCQRLEFQY QGNTFYFRPP GKFEQFLTVS
     DMLSKCLLRV NDEVKEINFL EMPAFVLKWA NDIFTTLAIP GPNGPITGIG NIIGLFE