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GP2D_CHLTH
ID   GP2D_CHLTH              Reviewed;         354 AA.
AC   P0CE17; P08782; Q46429; Q46430;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-MAR-2010, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Virulence plasmid protein pGP2-D;
DE   AltName: Full=Protein P-4;
OS   Chlamydia trachomatis.
OG   Plasmid pLGV440, Plasmid pCHL1, and Plasmid pCTT1.
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=813;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=L1/440/LN; PLASMID=pLGV440;
RX   PubMed=2836808; DOI=10.1093/nar/16.9.4053;
RA   Hatt C., Ward M.E., Clarke I.N.;
RT   "Analysis of the entire nucleotide sequence of the cryptic plasmid of
RT   Chlamydia trachomatis serovar L1. Evidence for involvement in DNA
RT   replication.";
RL   Nucleic Acids Res. 16:4053-4067(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=D/GO/86; PLASMID=pCHL1;
RX   PubMed=2194229; DOI=10.1016/0147-619x(90)90034-a;
RA   Comanducci M., Ricci S., Cevenini R., Ratti G.;
RT   "Diversity of the Chlamydia trachomatis common plasmid in biovars with
RT   different pathogenicity.";
RL   Plasmid 23:149-154(1990).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Serotype B; PLASMID=pCTT1;
RX   PubMed=3444859; DOI=10.1016/0147-619x(87)90063-1;
RA   Sriprakash K.S., Macavoy E.S.;
RT   "Characterization and sequence of a plasmid from the trachoma biovar of
RT   Chlamydia trachomatis.";
RL   Plasmid 18:205-214(1987).
CC   -!- MISCELLANEOUS: PGP2-D is required for growth within mammalian cells.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB02588.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; X06707; CAA29893.1; -; Genomic_DNA.
DR   EMBL; J03321; AAA91570.1; -; Genomic_DNA.
DR   EMBL; M19487; AAB02587.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; M19487; AAB02588.1; ALT_FRAME; Genomic_DNA.
DR   PIR; S02220; S02220.
DR   RefSeq; NP_040383.1; NC_001372.1.
DR   RefSeq; WP_012209815.1; NZ_CVNC01000027.1.
DR   RefSeq; YP_001569037.1; NC_010029.2.
DR   RefSeq; YP_001654091.1; NC_010286.1.
DR   RefSeq; YP_002842070.1; NC_012631.1.
DR   AlphaFoldDB; P0CE17; -.
DR   OMA; LKWLTKH; -.
PE   4: Predicted;
KW   Plasmid.
FT   CHAIN           1..354
FT                   /note="Virulence plasmid protein pGP2-D"
FT                   /id="PRO_0000218341"
FT   VARIANT         168
FT                   /note="E -> V (in plasmid pCTT1)"
FT   VARIANT         190
FT                   /note="S -> P (in plasmid pCHL1)"
FT   VARIANT         264
FT                   /note="F -> L (in plasmid pCHL1 and plasmid pCTT1)"
FT   CONFLICT        348..350
FT                   /note="Missing (in Ref. 3)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   354 AA;  41425 MW;  9824B81FC6722E8A CRC64;
     MVNYSNCHFI KSPIHLENQK FGRRPGQSIK ISPKLAQNGM VEVIGLDFLS SHYHALAAIQ
     RLLTATNYKG NTKGVVLSRE SNSFQFEGWI PRIRFTKTEF LEAYGVKRYK TSRNKYEFSG
     KEAETALEAL YHLGHQPFLI VATRTRWTNG TQIVDRYQTL SPIIRIYEGW EGLTDEENID
     IDLTPFNSPS TRKHKGFVVE PCPILVDQIE SYFVIKPANV YQEIKMRFPN ASKYAYTFID
     WVITAAAKKR RKLTKDNSWP ENLFLNVNVK SLAYILRMNR YICTRNWKKI ELAIDKCIEI
     AIQLGWLSRR KRIEFLDSSK LSKKEILYLN KERFEEITKK SKEQMEQLEQ ESIN
 
 
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