GP2D_CHLTH
ID GP2D_CHLTH Reviewed; 354 AA.
AC P0CE17; P08782; Q46429; Q46430;
DT 02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 02-MAR-2010, sequence version 1.
DT 25-MAY-2022, entry version 36.
DE RecName: Full=Virulence plasmid protein pGP2-D;
DE AltName: Full=Protein P-4;
OS Chlamydia trachomatis.
OG Plasmid pLGV440, Plasmid pCHL1, and Plasmid pCTT1.
OC Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=813;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=L1/440/LN; PLASMID=pLGV440;
RX PubMed=2836808; DOI=10.1093/nar/16.9.4053;
RA Hatt C., Ward M.E., Clarke I.N.;
RT "Analysis of the entire nucleotide sequence of the cryptic plasmid of
RT Chlamydia trachomatis serovar L1. Evidence for involvement in DNA
RT replication.";
RL Nucleic Acids Res. 16:4053-4067(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=D/GO/86; PLASMID=pCHL1;
RX PubMed=2194229; DOI=10.1016/0147-619x(90)90034-a;
RA Comanducci M., Ricci S., Cevenini R., Ratti G.;
RT "Diversity of the Chlamydia trachomatis common plasmid in biovars with
RT different pathogenicity.";
RL Plasmid 23:149-154(1990).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Serotype B; PLASMID=pCTT1;
RX PubMed=3444859; DOI=10.1016/0147-619x(87)90063-1;
RA Sriprakash K.S., Macavoy E.S.;
RT "Characterization and sequence of a plasmid from the trachoma biovar of
RT Chlamydia trachomatis.";
RL Plasmid 18:205-214(1987).
CC -!- MISCELLANEOUS: PGP2-D is required for growth within mammalian cells.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB02588.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; X06707; CAA29893.1; -; Genomic_DNA.
DR EMBL; J03321; AAA91570.1; -; Genomic_DNA.
DR EMBL; M19487; AAB02587.1; ALT_FRAME; Genomic_DNA.
DR EMBL; M19487; AAB02588.1; ALT_FRAME; Genomic_DNA.
DR PIR; S02220; S02220.
DR RefSeq; NP_040383.1; NC_001372.1.
DR RefSeq; WP_012209815.1; NZ_CVNC01000027.1.
DR RefSeq; YP_001569037.1; NC_010029.2.
DR RefSeq; YP_001654091.1; NC_010286.1.
DR RefSeq; YP_002842070.1; NC_012631.1.
DR AlphaFoldDB; P0CE17; -.
DR OMA; LKWLTKH; -.
PE 4: Predicted;
KW Plasmid.
FT CHAIN 1..354
FT /note="Virulence plasmid protein pGP2-D"
FT /id="PRO_0000218341"
FT VARIANT 168
FT /note="E -> V (in plasmid pCTT1)"
FT VARIANT 190
FT /note="S -> P (in plasmid pCHL1)"
FT VARIANT 264
FT /note="F -> L (in plasmid pCHL1 and plasmid pCTT1)"
FT CONFLICT 348..350
FT /note="Missing (in Ref. 3)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 354 AA; 41425 MW; 9824B81FC6722E8A CRC64;
MVNYSNCHFI KSPIHLENQK FGRRPGQSIK ISPKLAQNGM VEVIGLDFLS SHYHALAAIQ
RLLTATNYKG NTKGVVLSRE SNSFQFEGWI PRIRFTKTEF LEAYGVKRYK TSRNKYEFSG
KEAETALEAL YHLGHQPFLI VATRTRWTNG TQIVDRYQTL SPIIRIYEGW EGLTDEENID
IDLTPFNSPS TRKHKGFVVE PCPILVDQIE SYFVIKPANV YQEIKMRFPN ASKYAYTFID
WVITAAAKKR RKLTKDNSWP ENLFLNVNVK SLAYILRMNR YICTRNWKKI ELAIDKCIEI
AIQLGWLSRR KRIEFLDSSK LSKKEILYLN KERFEEITKK SKEQMEQLEQ ESIN