ID   GP2_EHV1V               Reviewed;         866 AA.
AC   Q6S6W0;
DT   15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   29-SEP-2021, entry version 50.
DE   RecName: Full=Glycoprotein gp2;
DE   AltName: Full=Glycoprotein X;
DE            Short=GpX;
DE   Flags: Precursor;
GN   OrderedLocusNames=71;
OS   Equine herpesvirus 1 (strain V592) (EHV-1) (Equine abortion virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX   NCBI_TaxID=310273;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1] {ECO:0000305, ECO:0000312|EMBL:AAS45959.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Davis-Poynter N., Nugent J., Birch-Machin I., Allen G.P.;
RL   Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Virulence factor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000305}; Single-pass
CC       membrane protein {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY464052; AAS45959.1; -; Genomic_DNA.
DR   Proteomes; UP000008296; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
DR   InterPro; IPR010278; Varicellovirus_Gp2_glycop.
DR   Pfam; PF05955; Herpes_gp2; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Signal; Transmembrane; Transmembrane helix; Virion;
KW   Virulence.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..866
FT                   /note="Glycoprotein gp2"
FT                   /id="PRO_0000038297"
FT   TRANSMEM        835..855
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          24..185
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          319..619
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        319..560
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        48
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        518
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        611
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        659
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   866 AA;  86510 MW;  260CB0770A8C09A2 CRC64;
     MGFIYARKLL LCMAVSIYAI GSTTTTETTT SSSSTSGSGQ STSSGTTNSS SSPTTSPPTT
     SSSPPTSTHT SSPSSTSTQS SSTAATSSSA PSTASSTTSI PTSTSTETTT TTPTASTTTP
     TTTTAAPTTA ATTTAVTTAA STSAETTTAT ATATSTPTTT TPTSTTTTTA TTTVPTTAST
     TTDTTTAATT TAATTTAATT TAATTTAATT TAATTTAATT TAATTTAATT TAATTTAATT
     SSATTAATTS STTTAATTTA ATTTAATTTA ATTTAATTTA ATTTAATTTA ATTTAATTTA
     ATTTAATTTA ATTTAATTTA ATTTAATTTG SPTSGSTSTT GASTSTPSAS TATSATPTST
     STSAAATTST PTPTSAATSA ESTTEAPTST PTTDTTTPSE ATTATTSPES TTVSASTTSA
     TTTAFTTESH TSPDSSTGST STAEPSSTFT LTPSTATPST DQFTGSSAST ESDSTDSSTV
     PTTGTESITE SSSTTEASTN LGSSTYESTE ALETPDGNTT SGNTTPSPSP RTPSFADTQQ
     TPDNGVSTQH TTINDHTTAN AQKHAGHHRG RAGGRRGSPQ GGSHTTPHPD RLTPSPDDTY
     DDDTNHPNGR NNSIEIVPQL PPDRPIIELG VATLRKNFME ASCTVETNSG LAIFWKIGNA
     SVDAFNRGTT HTRLMRNGVP VYALVSTLRV PWLNVIPLTK ITCAACPTNL VAGDGVDLNS
     CTTKSTTIPC PGQQRTHIFF SAKGDRAVCI TSELVSQPTI TWSVGSDRLR NDGFSQTWYG
     IQPGVCGILR SEVRIHRTTW RFGSTSKDYL CEVSASDSKT SDYKVLPNAH STSNFALVAA
     TTLTVTILCL LCCLYCMLTR PRASVY