GP3D_CHLTH
ID GP3D_CHLTH Reviewed; 264 AA.
AC P0CE18; P08783; P08784; P10557; Q46431;
DT 02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 02-MAR-2010, sequence version 1.
DT 25-MAY-2022, entry version 47.
DE RecName: Full=Virulence plasmid protein pGP3-D;
DE AltName: Full=Proteins P-6/P-7;
OS Chlamydia trachomatis.
OG Plasmid pLGV440, Plasmid pCHL1, and Plasmid pCTT1.
OC Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=813;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=L1/440/LN; PLASMID=pLGV440;
RX PubMed=2836808; DOI=10.1093/nar/16.9.4053;
RA Hatt C., Ward M.E., Clarke I.N.;
RT "Analysis of the entire nucleotide sequence of the cryptic plasmid of
RT Chlamydia trachomatis serovar L1. Evidence for involvement in DNA
RT replication.";
RL Nucleic Acids Res. 16:4053-4067(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=D/GO/86; PLASMID=pCHL1;
RX PubMed=2194229; DOI=10.1016/0147-619x(90)90034-a;
RA Comanducci M., Ricci S., Cevenini R., Ratti G.;
RT "Diversity of the Chlamydia trachomatis common plasmid in biovars with
RT different pathogenicity.";
RL Plasmid 23:149-154(1990).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Serotype B; PLASMID=pCTT1;
RX PubMed=3444859; DOI=10.1016/0147-619x(87)90063-1;
RA Sriprakash K.S., Macavoy E.S.;
RT "Characterization and sequence of a plasmid from the trachoma biovar of
RT Chlamydia trachomatis.";
RL Plasmid 18:205-214(1987).
CC -!- MISCELLANEOUS: PGP3-D is required for growth within mammalian cells.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB02589.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; X06707; CAA29894.1; -; Genomic_DNA.
DR EMBL; J03321; AAA91571.1; -; Genomic_DNA.
DR EMBL; M19487; AAB02589.1; ALT_FRAME; Genomic_DNA.
DR PIR; S01922; S01922.
DR RefSeq; NP_040384.1; NC_001372.1.
DR RefSeq; WP_012209816.1; NZ_CVNC01000027.1.
DR RefSeq; YP_001569038.1; NC_010029.2.
DR RefSeq; YP_001654090.1; NC_010286.1.
DR RefSeq; YP_002842026.1; NC_012625.1.
DR RefSeq; YP_002842034.1; NC_012626.1.
DR RefSeq; YP_002842063.1; NC_012630.1.
DR RefSeq; YP_002842071.1; NC_012631.1.
DR PDB; 6GJT; X-ray; 1.98 A; A/B/C/D/E/F=1-264.
DR PDBsum; 6GJT; -.
DR AlphaFoldDB; P0CE18; -.
DR SMR; P0CE18; -.
DR OMA; NADSMFL; -.
DR PHI-base; PHI:4562; -.
DR InterPro; IPR008444; Chlamydia_pGP3.
DR InterPro; IPR033758; pGP3_C.
DR Pfam; PF05475; Chlam_vir; 1.
DR PIRSF; PIRSF016070; Chlamydia_vir; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Plasmid.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..264
FT /note="Virulence plasmid protein pGP3-D"
FT /id="PRO_0000218344"
FT VARIANT 12
FT /note="Q -> E (in plasmid PCHL1 and plasmid pCTT1)"
FT VARIANT 61
FT /note="P -> S (in plasmid PCHL1 and plasmid pCTT1)"
FT VARIANT 86
FT /note="D -> N (in plasmid pCTT1)"
FT VARIANT 90
FT /note="G -> D (in plasmid pCHL1 and plasmid pCTT1)"
FT VARIANT 109
FT /note="T -> K (in plasmid pCHL1)"
FT VARIANT 138
FT /note="R -> S (in plasmid pCHL1 and plasmid pCTT1)"
FT VARIANT 189
FT /note="K -> N (in plasmid pCTT1)"
FT VARIANT 191
FT /note="Y -> C (in plasmid pCHL1 and plasmid pCTT1)"
FT VARIANT 201
FT /note="V -> I (in plasmid pCHL1)"
FT VARIANT 210
FT /note="R -> S (in plasmid pCHL1 and plasmid pCTT1)"
FT VARIANT 212
FT /note="I -> T (in plasmid pCHL1 and plasmid pCTT1)"
FT STRAND 5..9
FT /evidence="ECO:0007829|PDB:6GJT"
FT STRAND 12..16
FT /evidence="ECO:0007829|PDB:6GJT"
FT HELIX 101..108
FT /evidence="ECO:0007829|PDB:6GJT"
FT STRAND 120..125
FT /evidence="ECO:0007829|PDB:6GJT"
FT STRAND 129..131
FT /evidence="ECO:0007829|PDB:6GJT"
FT TURN 137..141
FT /evidence="ECO:0007829|PDB:6GJT"
FT STRAND 145..154
FT /evidence="ECO:0007829|PDB:6GJT"
FT STRAND 162..172
FT /evidence="ECO:0007829|PDB:6GJT"
FT STRAND 174..184
FT /evidence="ECO:0007829|PDB:6GJT"
FT STRAND 191..201
FT /evidence="ECO:0007829|PDB:6GJT"
FT STRAND 203..212
FT /evidence="ECO:0007829|PDB:6GJT"
FT STRAND 215..217
FT /evidence="ECO:0007829|PDB:6GJT"
FT STRAND 219..230
FT /evidence="ECO:0007829|PDB:6GJT"
FT STRAND 233..237
FT /evidence="ECO:0007829|PDB:6GJT"
FT HELIX 244..246
FT /evidence="ECO:0007829|PDB:6GJT"
FT STRAND 251..258
FT /evidence="ECO:0007829|PDB:6GJT"
SQ SEQUENCE 264 AA; 27923 MW; CE62244839F8971B CRC64;
MGNSGFYLYN TQNCVFADNI KVGQMTEPLK DQQIILGTTS TPVAAKMTAS DGISLTVSNN
PSTNASITIG LDAEKAYQLI LEKLGDQILG GIADTIVDST VQDILDKITT DPSLGLLKAF
NNFPITNKIQ CNGLFTPRNI ETLLGGTEIG KFTVTPKSSG SMFLVSADII ASRMEGGVVL
ALVREGDSKP YAISYGYSSG VPNLCSLRTR IINTGLTPTT YSLRVGGLES GVVWVNALSN
GNDILGITNT SNVSFLEVIP QTNA
