ID   GP57_BPT4               Reviewed;          80 AA.
AC   P04532;
DT   13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   02-JUN-2021, entry version 78.
DE   RecName: Full=Tail fiber assembly helper protein;
DE   AltName: Full=Gene product 57;
DE            Short=gp57;
GN   Name=57; Synonyms=57A;
OS   Enterobacteria phage T4 (Bacteriophage T4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
OX   NCBI_TaxID=10665;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=4057254; DOI=10.1016/0022-2836(85)90071-3;
RA   Broida J., Abelson J.;
RT   "Sequence organization and control of transcription in the bacteriophage T4
RT   tRNA region.";
RL   J. Mol. Biol. 185:545-563(1985).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7063418; DOI=10.1093/nar/10.3.1105;
RA   Herrmann R.;
RT   "Nucleotide sequence of the bacteriophage T4 gene 57 and a deduced amino
RT   acid sequence.";
RL   Nucleic Acids Res. 10:1105-1112(1982).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12626685; DOI=10.1128/mmbr.67.1.86-156.2003;
RA   Miller E.S., Kutter E., Mosig G., Arisaka F., Kunisawa T., Ruger W.;
RT   "Bacteriophage T4 genome.";
RL   Microbiol. Mol. Biol. Rev. 67:86-156(2003).
RN   [4]
RP   PROTEIN SEQUENCE, FUNCTION, AND CHARACTERIZATION.
RX   PubMed=9068627; DOI=10.1128/jb.179.6.1846-1851.1997;
RA   Matsui T., Griniuviene B., Goldberg E., Tsugita A., Tanaka N., Arisaka F.;
RT   "Isolation and characterization of a molecular chaperone, gp57A, of
RT   bacteriophage T4.";
RL   J. Bacteriol. 179:1846-1851(1997).
RN   [5]
RP   PROTEIN SEQUENCE OF 2-8, CHARACTERIZATION, CRYSTALLIZATION, IDENTIFICATION,
RP   AND FUNCTION.
RX   PubMed=8892827; DOI=10.1128/jb.178.21.6258-6265.1996;
RA   Hashemolhosseini S., Stierhof Y.D., Hindennach I., Henning U.;
RT   "Characterization of the helper proteins for the assembly of tail fibers of
RT   coliphages T4 and lambda.";
RL   J. Bacteriol. 178:6258-6265(1996).
RN   [6]
RP   FUNCTION.
RX   PubMed=4944598; DOI=10.1016/0022-2836(71)90149-5;
RA   Ward S., Dickson R.C.;
RT   "Assembly of bacteriophage T4 tail fibers. 3. Genetic control of the major
RT   tail fiber polypeptides.";
RL   J. Mol. Biol. 62:479-492(1971).
RN   [7]
RP   FUNCTION.
RX   PubMed=7038383; DOI=10.1007/bf00271208;
RA   Herrmann R., Wood W.B.;
RT   "Assembly of bacteriophage T4 tail fibers: identification and
RT   characterization of the nonstructural protein gp57.";
RL   Mol. Gen. Genet. 184:125-132(1981).
RN   [8]
RP   SUBUNIT.
RX   PubMed=14507723; DOI=10.1016/s0006-3495(03)74683-9;
RA   Ali S.A., Iwabuchi N., Matsui T., Hirota K., Kidokoro S., Arai M.,
RA   Kuwajima K., Schuck P., Arisaka F.;
RT   "Reversible and fast association equilibria of a molecular chaperone,
RT   gp57A, of bacteriophage T4.";
RL   Biophys. J. 85:2606-2618(2003).
RN   [9]
RP   FUNCTION.
RX   PubMed=19913618; DOI=10.1016/j.pep.2009.11.005;
RA   Bartual S.G., Garcia-Doval C., Alonso J., Schoehn G., van Raaij M.J.;
RT   "Two-chaperone assisted soluble expression and purification of the
RT   bacteriophage T4 long tail fibre protein gp37.";
RL   Protein Expr. Purif. 70:116-121(2010).
CC   -!- FUNCTION: Chaperone essential for folding and oligomerization of both
CC       long and short tail fibers. Required for the assembly of gp34, gp36 and
CC       gp37 (components of the long tail fiber) and p12 (the subunit of the
CC       short tail fiber). Together with gp38, participates in the formation of
CC       the distal part of the long fibers. {ECO:0000269|PubMed:19913618,
CC       ECO:0000269|PubMed:4944598, ECO:0000269|PubMed:7038383,
CC       ECO:0000269|PubMed:8892827, ECO:0000269|PubMed:9068627}.
CC   -!- SUBUNIT: Homotrimer. Homohexamer. {ECO:0000269|PubMed:14507723}.
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DR   EMBL; X03016; CAA26801.1; -; Genomic_DNA.
DR   EMBL; AF158101; AAD42500.1; -; Genomic_DNA.
DR   PIR; B92919; ZABPT4.
DR   RefSeq; NP_049751.1; NC_000866.4.
DR   SMR; P04532; -.
DR   DNASU; 1258624; -.
DR   GeneID; 1258624; -.
DR   KEGG; vg:1258624; -.
DR   Proteomes; UP000009087; Genome.
DR   GO; GO:0098004; P:virus tail fiber assembly; IDA:UniProtKB.
DR   InterPro; IPR020159; Phage_Gp57.
DR   Pfam; PF17594; GP57; 1.
PE   1: Evidence at protein level;
KW   Chaperone; Direct protein sequencing; Reference proteome;
KW   Viral release from host cell; Viral tail assembly;
KW   Viral tail fiber assembly.
FT   INIT_MET        1
FT                   /note="Removed; by host"
FT                   /evidence="ECO:0000269|PubMed:8892827"
FT   CHAIN           2..80
FT                   /note="Tail fiber assembly helper protein"
FT                   /id="PRO_0000164992"
FT   CONFLICT        6
FT                   /note="V -> I (in Ref. 4; AA sequence and 5; AA sequence)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   80 AA;  8731 MW;  43CF9FC978765EB7 CRC64;
     MSEQTVEQKL SAEIVTLKSR ILDTQDQAAR LMEESKILQG TLAEIARAVG ITGDTIKVEE
     IVEAVKNLTA ESADEAKDEE