ID   GP68_BPT4               Reviewed;         141 AA.
AC   P04538;
DT   13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
DT   13-AUG-1987, sequence version 1.
DT   29-SEP-2021, entry version 73.
DE   RecName: Full=Prohead assembly protein gp68;
DE   AltName: Full=Gene product 68;
DE            Short=gp68;
DE   Contains:
DE     RecName: Full=Protein gp68*;
GN   Name=gp68;
OS   Enterobacteria phage T4 (Bacteriophage T4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
OX   NCBI_TaxID=10665;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RX   PubMed=6512858; DOI=10.1016/0022-2836(84)90073-1;
RA   Keller B., Sengstag C., Kellenberger E., Bickle T.A.;
RT   "Gene 68, a new bacteriophage T4 gene which codes for the 17K prohead core
RT   protein is involved in head size determination.";
RL   J. Mol. Biol. 179:415-430(1984).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12626685; DOI=10.1128/mmbr.67.1.86-156.2003;
RA   Miller E.S., Kutter E., Mosig G., Arisaka F., Kunisawa T., Ruger W.;
RT   "Bacteriophage T4 genome.";
RL   Microbiol. Mol. Biol. Rev. 67:86-156(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-13.
RX   PubMed=7154087; DOI=10.1016/0022-2836(82)90402-8;
RA   Voelker T.A., Gafner J., Bickle T.A., Showe M.K.;
RT   "Gene 67, a new, essential bacteriophage T4 head gene codes for a prehead
RT   core component, PIP. I. Genetic mapping and DNA sequence.";
RL   J. Mol. Biol. 161:479-489(1982).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 24-45.
RX   PubMed=6287296; DOI=10.1038/299369a0;
RA   Christensen A.C., Young E.T.;
RT   "T4 late transcripts are initiated near a conserved DNA sequence.";
RL   Nature 299:369-371(1982).
RN   [5]
RP   CLEAVAGE SITE.
RX   PubMed=3912510; DOI=10.1016/0022-2836(85)90138-x;
RA   Keller B., Kellenberger E., Bickle T.A., Tsugita A.;
RT   "Determination of the cleavage site of the phage T4 prohead protease in
RT   gene product 68. Influence of protein secondary structure on cleavage
RT   specificity.";
RL   J. Mol. Biol. 186:665-667(1985).
CC   -!- FUNCTION: Plays a role in the phage head size determination. About ten
CC       copies of gp68* are found in the mature phage head.
CC       {ECO:0000269|PubMed:6512858}.
CC   -!- SUBCELLULAR LOCATION: [Protein gp68*]: Virion.
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DR   EMBL; X01414; CAA25656.1; -; Genomic_DNA.
DR   EMBL; AF158101; AAD42516.1; -; Genomic_DNA.
DR   EMBL; J02512; AAA32521.1; -; Genomic_DNA.
DR   PIR; A04340; HIBPX4.
DR   RefSeq; NP_049784.1; NC_000866.4.
DR   SMR; P04538; -.
DR   GeneID; 1258769; -.
DR   KEGG; vg:1258769; -.
DR   Proteomes; UP000009087; Genome.
DR   InterPro; IPR016415; Phage_T4_Gp68.
DR   PIRSF; PIRSF004377; Phage_prohead_core; 1.
PE   1: Evidence at protein level;
KW   Reference proteome; Virion.
FT   CHAIN           1..141
FT                   /note="Prohead assembly protein gp68"
FT                   /id="PRO_0000430197"
FT   CHAIN           17..141
FT                   /note="Protein gp68*"
FT                   /id="PRO_0000003329"
FT   REGION          80..141
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        123..141
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   SITE            16..17
FT                   /note="Cleavage; by prohead core protease GP21"
SQ   SEQUENCE   141 AA;  15873 MW;  8E5799D52D8E4709 CRC64;
     MLLIPETHEL VLENVEALIP EAQGRFDELS SALNKDDINT IVENMLDDET DLAVALASIN
     ENMPLNEFIV KHVSARGEIT RTKDRKTRER NAFQTTGLSK AKRRQIARKA TKTKIANPAG
     QSRAQRKRKK ALKRRKALGL S