ID   GP6D_CHLTH              Reviewed;         247 AA.
AC   P10560; P08787; Q46433;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Virulence plasmid protein pGP6-D;
DE   AltName: Full=Protein P-10;
OS   Chlamydia trachomatis.
OG   Plasmid pLGV440, Plasmid pCHL1, and Plasmid pCTT1.
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=813;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=L2/434/Bu; PLASMID=pLGV440;
RX   PubMed=2845228; DOI=10.1111/j.1365-2958.1988.tb00060.x;
RA   Comanducci M., Ricci S., Ratti G.;
RT   "The structure of a plasmid of Chlamydia trachomatis believed to be
RT   required for growth within mammalian cells.";
RL   Mol. Microbiol. 2:531-538(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=L1/440/LN; PLASMID=pLGV440;
RX   PubMed=2836808; DOI=10.1093/nar/16.9.4053;
RA   Hatt C., Ward M.E., Clarke I.N.;
RT   "Analysis of the entire nucleotide sequence of the cryptic plasmid of
RT   Chlamydia trachomatis serovar L1. Evidence for involvement in DNA
RT   replication.";
RL   Nucleic Acids Res. 16:4053-4067(1988).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=D/GO/86; PLASMID=pCHL1;
RX   PubMed=2194229; DOI=10.1016/0147-619x(90)90034-a;
RA   Comanducci M., Ricci S., Cevenini R., Ratti G.;
RT   "Diversity of the Chlamydia trachomatis common plasmid in biovars with
RT   different pathogenicity.";
RL   Plasmid 23:149-154(1990).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Serotype B; PLASMID=pCTT1;
RX   PubMed=3444859; DOI=10.1016/0147-619x(87)90063-1;
RA   Sriprakash K.S., Macavoy E.S.;
RT   "Characterization and sequence of a plasmid from the trachoma biovar of
RT   Chlamydia trachomatis.";
RL   Plasmid 18:205-214(1987).
CC   -!- MISCELLANEOUS: pGP6-D is required for growth within mammalian cells.
CC   -!- MISCELLANEOUS: The sequence shown is that of plasmid pLGV440.
CC   -!- SIMILARITY: Belongs to the UPF0137 (pGP6-D) family. {ECO:0000305}.
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DR   EMBL; X07547; CAA30426.1; -; Genomic_DNA.
DR   EMBL; X06707; CAA29897.1; -; Genomic_DNA.
DR   EMBL; J03321; AAA91574.1; -; Genomic_DNA.
DR   EMBL; M19487; AAB02591.1; -; Genomic_DNA.
DR   PIR; S01924; S01924.
DR   RefSeq; NP_040387.1; NC_001372.1.
DR   RefSeq; WP_010889889.1; NZ_CVNT01000004.1.
DR   RefSeq; WP_012209819.1; NZ_CVND01000040.1.
DR   RefSeq; YP_001569041.1; NC_010029.2.
DR   RefSeq; YP_001654087.1; NC_010286.1.
DR   RefSeq; YP_002842029.1; NC_012625.1.
DR   RefSeq; YP_002842037.1; NC_012626.1.
DR   RefSeq; YP_002842066.1; NC_012630.1.
DR   RefSeq; YP_002842074.1; NC_012631.1.
DR   AlphaFoldDB; P10560; -.
DR   OMA; VMKRING; -.
DR   InterPro; IPR005350; UPF0137.
DR   Pfam; PF03677; UPF0137; 1.
PE   3: Inferred from homology;
KW   Plasmid.
FT   CHAIN           1..247
FT                   /note="Virulence plasmid protein pGP6-D"
FT                   /id="PRO_0000220776"
FT   VARIANT         9
FT                   /note="N -> D (in plasmid pCHL1 and plasmid pCTT1)"
FT   VARIANT         47
FT                   /note="Q -> R (in plasmid pCHL1 and plasmid pCTT1)"
FT   VARIANT         183..186
FT                   /note="VLDQ -> CWIE (in plasmid pCTT1)"
FT   VARIANT         194
FT                   /note="K -> T (in plasmid pCTT1)"
FT   VARIANT         205
FT                   /note="S -> L (in plasmid pCTT1)"
FT   VARIANT         222
FT                   /note="M -> I (in plasmid pCTT1)"
SQ   SEQUENCE   247 AA;  28307 MW;  F1FA11F29037C221 CRC64;
     MNKLKKEANV FFKKNQTAAS LDFKKTLPSI ELFSATLNSE ESQSLDQLFL SESQNYSDEE
     FYQEDILAVK LLTGQIKSIQ KQHVLLLGEK IYNARKILSK DHFSSTTFSS WIELVFRTKS
     SAYNALAYYE LFINLPNQTL QKEFQSIPYK SAYILAARKG DLKTKVDVIG KVCGMSNSSA
     IRVLDQFLPS SRNKDVRETI DKSDSEKNRQ LSDFLIEILR IMCSGVSLSS YNENLLQQLF
     ELFKQKS