ID   GP7D_CHLPS              Reviewed;         307 AA.
AC   Q46257;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Virulence plasmid integrase pGP7-D;
OS   Chlamydia psittaci (Chlamydophila psittaci).
OG   Plasmid pCpA1.
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=83554;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=N352;
RX   PubMed=9202459; DOI=10.1099/00221287-143-6-1847;
RA   Thomas N.S., Lusher M., Storey C.C., Clarke I.N.;
RT   "Plasmid diversity in Chlamydia.";
RL   Microbiology 143:1847-1854(1997).
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family. {ECO:0000305}.
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DR   EMBL; X62475; CAA44333.1; -; Genomic_DNA.
DR   PIR; S18142; A39999.
DR   RefSeq; NP_052324.1; NC_002117.1.
DR   RefSeq; WP_010891146.1; NZ_PJQA01000017.1.
DR   AlphaFoldDB; Q46257; -.
DR   SMR; Q46257; -.
DR   GeneID; 12242268; -.
DR   GeneID; 66226167; -.
DR   OMA; SGLSHYH; -.
DR   PRO; PR:Q46257; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.443.10; -; 1.
DR   InterPro; IPR044068; CB.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; SSF56349; 1.
DR   PROSITE; PS51900; CB; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   DNA integration; DNA recombination; DNA-binding; Plasmid;
KW   Viral genome integration; Virus entry into host cell.
FT   CHAIN           1..307
FT                   /note="Virulence plasmid integrase pGP7-D"
FT                   /id="PRO_0000197562"
FT   DOMAIN          14..101
FT                   /note="Core-binding (CB)"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01248"
FT   DOMAIN          129..304
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        188
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        256
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        259
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        291
FT                   /note="O-(3'-phospho-DNA)-tyrosine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
SQ   SEQUENCE   307 AA;  35049 MW;  5C6677851B31B6EB CRC64;
     MSGLSHHHKS RLFLTVLEAA NVWLATLSPI TRKNYASGIK FLVANHILDG SMKLEGLVCC
     DHCDILNRIK SLTFTYSGKP VSEASKQARA ACYISFTKFL YRLTKGVIKH ASPSKDFGNP
     TFYKIRDKVK TEFISKREWL LFFDALKKIS FRDYLIGKLI IQGVRKLTEV ISLRTEDISF
     AKNQVTFKVK KRQNRYQEVK VSYPNFLMQE LQDYLGNREG WVFVSGEGQQ VAINQVYYYF
     KLAEGDINSP IKVTPHVLRA SALAYLKKMG FADQEIMRVS CLSSTQMLSA YDTGMTDNLT
     SQLPLIF