GP8_BPN4
ID GP8_BPN4 Reviewed; 71 AA.
AC A0MZA0;
DT 24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT 12-DEC-2006, sequence version 1.
DT 29-SEP-2021, entry version 24.
DE RecName: Full=Gene product 8 {ECO:0000305};
DE Short=gp8;
OS Enterobacteria phage N4 (Bacteriophage N4).
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Caudovirales; Schitoviridae; Enquatrovirinae; Enquatrovirus.
OX NCBI_TaxID=10752 {ECO:0000312|Proteomes:UP000001789};
OH NCBI_TaxID=562; Escherichia coli.
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hendrix R.W., Rothman-Denes L., Hatfull G.F., Lawrence J.G., Pedulla M.;
RT "Genome sequence and analysis of bacteriophage N4.";
RL Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP FUNCTION.
RX PubMed=21205014; DOI=10.1111/j.1365-2958.2010.07526.x;
RA Yano S.T., Rothman-Denes L.B.;
RT "A phage-encoded inhibitor of Escherichia coli DNA replication targets the
RT DNA polymerase clamp loader.";
RL Mol. Microbiol. 79:1325-1338(2011).
CC -!- FUNCTION: Targets the host DNA sliding clamp and inhibits host DNA
CC replication. {ECO:0000269|PubMed:21205014}.
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DR EMBL; EF056009; ABK54379.1; -; Genomic_DNA.
DR RefSeq; YP_950486.1; NC_008720.1.
DR GeneID; 5075662; -.
DR KEGG; vg:5075662; -.
DR Proteomes; UP000001789; Genome.
DR GO; GO:0098673; P:inhibition of host DNA replication by virus; IEA:UniProtKB-KW.
DR GO; GO:0060153; P:modulation by virus of host cell cycle; IEA:UniProtKB-KW.
PE 4: Predicted;
KW Host-virus interaction; Inhibition of host DNA replication by virus;
KW Modulation of host cell cycle by virus; Reference proteome.
FT CHAIN 1..71
FT /note="Gene product 8"
FT /id="PRO_0000433214"
SQ SEQUENCE 71 AA; 8139 MW; D180111F325B57F3 CRC64;
MEQLNYGYKI KRNQVRGSWL FLVYGKPIYE LHRGEKSKTY YVTHIATGKT PACAGLLRDA
IMKACMLEGL L