ID   GPBL1_PONAB             Reviewed;         474 AA.
AC   Q5R9C3;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Vasculin-like protein 1;
DE   AltName: Full=GC-rich promoter-binding protein 1-like 1;
GN   Name=GPBP1L1;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Possible transcription factor. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the vasculin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR859466; CAH91637.1; -; mRNA.
DR   RefSeq; NP_001125962.1; NM_001132490.1.
DR   AlphaFoldDB; Q5R9C3; -.
DR   STRING; 9601.ENSPPYP00000001632; -.
DR   Ensembl; ENSPPYT00000001687; ENSPPYP00000001632; ENSPPYG00000001407.
DR   GeneID; 100172897; -.
DR   KEGG; pon:100172897; -.
DR   CTD; 60313; -.
DR   eggNOG; ENOG502QPN2; Eukaryota.
DR   GeneTree; ENSGT00420000029753; -.
DR   InParanoid; Q5R9C3; -.
DR   OrthoDB; 662557at2759; -.
DR   Proteomes; UP000001595; Chromosome 1.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR028128; Vasculin_fam.
DR   PANTHER; PTHR14339; PTHR14339; 1.
DR   Pfam; PF15337; Vasculin; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..474
FT                   /note="Vasculin-like protein 1"
FT                   /id="PRO_0000324117"
FT   REGION          17..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          91..191
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          238..371
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          453..474
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        25..42
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..120
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        132..163
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        259..280
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        291..313
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        314..363
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         49
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9HC44"
FT   MOD_RES         76
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9HC44"
FT   MOD_RES         202
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9HC44"
FT   MOD_RES         292
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q6NZP2"
FT   MOD_RES         301
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9HC44"
FT   MOD_RES         382
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9HC44"
SQ   SEQUENCE   474 AA;  52302 MW;  EA0A7497C120E9C7 CRC64;
     MAQHDFVPAW LNFSTPQSAK SPTATFEKHG EHLPRGEGRF GVSRRRHNSS DGFFNNGPLR
     TAGDSWHQPS LFRHDSVDSG VSKGAYAGIT GNPSGWHSSS RGHDGMSQRS GGGTGNHRHW
     NGSFHSRKGC AFQEKPPMEI REEKKEDKVE KLQFEEEDFP SLNPEAGKQH QPCRPIGTPS
     GVWENPPSAK QPSKMLVIKK VSKEDPAAAF SAAFTSPGSH HANGNKLSSV VPSVYKNLVP
     KPVPPPSKPN AWKANRMEHK SGSLSSSRES AFTSPISVTK PVVLASGAAL SSPKESPSST
     TPPIEISSSR LTKLTRRTTD RKSEFLKTLK DDRNGDFSEN RDCDKLEDLE DNSTPEPKEN
     GEEGCHQNGL ALPVVEEGEV LSHSLEAEHR LLKAMGWQEY PENDENCLPL TEDELKEFHM
     KTEQLRRNGF GKNGFLQSRS SSLFSPWRST CKAEFEDSDT ETSSSETSDD DAWK