ID   GPBP1_XENLA             Reviewed;         371 AA.
AC   Q6DD19;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Vasculin;
DE   AltName: Full=GC-rich promoter-binding protein 1;
GN   Name=gpbp1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Functions as a GC-rich promoter-specific transactivating
CC       transcription factor. {ECO:0000250|UniProtKB:Q6NXH3}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q6NXH3}.
CC   -!- SIMILARITY: Belongs to the vasculin family. {ECO:0000305}.
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DR   EMBL; BC077810; AAH77810.1; -; mRNA.
DR   RefSeq; NP_001086947.1; NM_001093478.1.
DR   AlphaFoldDB; Q6DD19; -.
DR   DNASU; 446782; -.
DR   GeneID; 446782; -.
DR   KEGG; xla:446782; -.
DR   CTD; 446782; -.
DR   Xenbase; XB-GENE-6255346; gpbp1.L.
DR   Proteomes; UP000186698; Chromosome 1L.
DR   Bgee; 446782; Expressed in testis and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR028128; Vasculin_fam.
DR   PANTHER; PTHR14339; PTHR14339; 2.
DR   Pfam; PF15337; Vasculin; 1.
PE   2: Evidence at transcript level;
KW   Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..371
FT                   /note="Vasculin"
FT                   /id="PRO_0000324113"
SQ   SEQUENCE   371 AA;  42247 MW;  3228CA74772EECC5 CRC64;
     MAQHDFAPAW LNFPTPPPST KPFLYAEKRS ESLGRSDCAF NVNRQRHNSS EAFDSSFGGN
     LKKREKNVWR PQSRSAAEPT WQREASLHLY SSNLQRVNSQ LRSERNTSEF DLTRSLDRED
     CKTFEAEDFS FLYPEHERGK KLFTARLWEY PMNAGSTSPQ MLGIKKGLMD DFSLSGYSIG
     VGNQSLPDKH WAGIKKEECK SLSKDNNIGS FYQDCPPENY IPNTSLHAEL LSVDPCSLEE
     EEDTHLNNRN DSCPEMDINL NFDENENSED NVNTLISGQI SPAYAQDGVL SSSLEAEFKL
     LREMGWQEND ESCAPLTEDE MREFQAISEQ LQKNGLRKHV FLRDALAFDL FQDAVQKEDS
     ETSSSDTSDD E