ID   GPBP1_XENTR             Reviewed;         375 AA.
AC   Q28FE5;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=Vasculin;
DE   AltName: Full=GC-rich promoter-binding protein 1;
GN   Name=gpbp1; ORFNames=TEgg008i02.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Functions as a GC-rich promoter-specific transactivating
CC       transcription factor. {ECO:0000250|UniProtKB:Q6NXH3}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q6NXH3}.
CC   -!- SIMILARITY: Belongs to the vasculin family. {ECO:0000305}.
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DR   EMBL; CR762006; CAJ83672.1; -; mRNA.
DR   RefSeq; NP_001037985.1; NM_001044520.1.
DR   AlphaFoldDB; Q28FE5; -.
DR   STRING; 8364.ENSXETP00000051889; -.
DR   PaxDb; Q28FE5; -.
DR   GeneID; 733777; -.
DR   KEGG; xtr:733777; -.
DR   CTD; 65056; -.
DR   Xenbase; XB-GENE-979389; gpbp1.
DR   eggNOG; ENOG502QR5W; Eukaryota.
DR   InParanoid; Q28FE5; -.
DR   OrthoDB; 662557at2759; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR028128; Vasculin_fam.
DR   PANTHER; PTHR14339; PTHR14339; 2.
DR   Pfam; PF15337; Vasculin; 1.
PE   2: Evidence at transcript level;
KW   Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..375
FT                   /note="Vasculin"
FT                   /id="PRO_0000324114"
FT   REGION          49..109
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          356..375
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        82..106
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   375 AA;  42107 MW;  4DC9A593C9CEE30A CRC64;
     MAQHDFAPAW LNFPTPPSST KPFLYSDKHS EGLGRSDCAF NVNRQRHSSS DAFDSAIGRP
     HGGNLAKREK IAWRPQSRAG AEPTWQRDTS PHPYSMKSQL HSENNTSEID LPRKVDREER
     KMFEVEDFSS LYPEHERGKN SFAAGLWEYP VSDRSRSSQM LGIKKGVKDD FSLSGYSIAA
     GNQSLPGKHW AGIKKEECKS LTKESSIGSS FYQDCPHEKY RPNTSLHAEL LAVTPCSLEG
     EEDTNLNNRN GSCPERDINL NFDENKISED NGNTLMSGQI SSAYPPDGVL SSSLEAEFRL
     LREMGWQEDS ENDETCAPLT EDEMKEFQAI SEQLQKNGLR KHVFLRNALA LDLFHDSVQK
     EDSETSSSSD TSDDE