ID   GPCP2_CAEEL             Reviewed;         796 AA.
AC   Q10003; G5ECZ6;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Putative glycerophosphocholine phosphodiesterase GPCPD1 homolog 2 {ECO:0000250|UniProtKB:Q9NPB8};
DE            EC=3.1.-.-;
GN   Name=gpcp-2 {ECO:0000312|WormBase:T05H10.7a};
GN   ORFNames=T05H10.7 {ECO:0000312|WormBase:T05H10.7a};
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=a {ECO:0000312|WormBase:T05H10.7a};
CC         IsoId=Q10003-1; Sequence=Displayed;
CC       Name=b {ECO:0000312|WormBase:T05H10.7b};
CC         IsoId=Q10003-2; Sequence=VSP_057654;
CC   -!- SIMILARITY: Belongs to the glycerophosphoryl diester phosphodiesterase
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; Z47812; CAA87796.1; -; Genomic_DNA.
DR   EMBL; Z47811; CAA87796.1; JOINED; Genomic_DNA.
DR   EMBL; BX284602; CAE48507.1; -; Genomic_DNA.
DR   PIR; T23238; T23238.
DR   RefSeq; NP_001022321.1; NM_001027150.1. [Q10003-1]
DR   RefSeq; NP_001022322.1; NM_001027151.2.
DR   AlphaFoldDB; Q10003; -.
DR   SMR; Q10003; -.
DR   BioGRID; 39627; 1.
DR   STRING; 6239.T05H10.7a; -.
DR   EPD; Q10003; -.
DR   PaxDb; Q10003; -.
DR   PeptideAtlas; Q10003; -.
DR   EnsemblMetazoa; T05H10.7a.1; T05H10.7a.1; WBGene00011511. [Q10003-1]
DR   EnsemblMetazoa; T05H10.7b.1; T05H10.7b.1; WBGene00011511. [Q10003-2]
DR   GeneID; 174296; -.
DR   KEGG; cel:CELE_T05H10.7; -.
DR   UCSC; T05H10.7b.1; c. elegans. [Q10003-1]
DR   CTD; 174296; -.
DR   WormBase; T05H10.7a; CE03637; WBGene00011511; gpcp-2. [Q10003-1]
DR   WormBase; T05H10.7b; CE01644; WBGene00011511; gpcp-2. [Q10003-2]
DR   eggNOG; KOG2421; Eukaryota.
DR   GeneTree; ENSGT00440000033970; -.
DR   InParanoid; Q10003; -.
DR   OMA; CFNPDIC; -.
DR   OrthoDB; 687958at2759; -.
DR   PhylomeDB; Q10003; -.
DR   PRO; PR:Q10003; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00011511; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR   GO; GO:0047389; F:glycerophosphocholine phosphodiesterase activity; IBA:GO_Central.
DR   GO; GO:2001070; F:starch binding; IEA:InterPro.
DR   GO; GO:0046475; P:glycerophospholipid catabolic process; IBA:GO_Central.
DR   CDD; cd05814; CBM20_Prei4; 1.
DR   Gene3D; 2.60.40.10; -; 1.
DR   Gene3D; 3.20.20.190; -; 1.
DR   InterPro; IPR013784; Carb-bd-like_fold.
DR   InterPro; IPR034839; CBM20_GPCPD1.
DR   InterPro; IPR002044; CBM_fam20.
DR   InterPro; IPR030395; GP_PDE_dom.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR   Pfam; PF00686; CBM_20; 1.
DR   Pfam; PF03009; GDPD; 1.
DR   SMART; SM01065; CBM_2; 1.
DR   SUPFAM; SSF49452; SSF49452; 1.
DR   SUPFAM; SSF51695; SSF51695; 1.
DR   PROSITE; PS51166; CBM20; 1.
DR   PROSITE; PS51704; GP_PDE; 1.
PE   3: Inferred from homology;
KW   Alternative splicing; Hydrolase; Reference proteome.
FT   CHAIN           1..796
FT                   /note="Putative glycerophosphocholine phosphodiesterase
FT                   GPCPD1 homolog 2"
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000065449"
FT   DOMAIN          78..195
FT                   /note="CBM20"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00594"
FT   DOMAIN          401..711
FT                   /note="GP-PDE"
FT   REGION          726..796
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        726..765
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        782..796
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         1..77
FT                   /note="Missing (in isoform b)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_057654"
SQ   SEQUENCE   796 AA;  90831 MW;  7BDF8E0A4D2AA9F1 CRC64;
     MHFTRRAVSP RASFVFDRHV GTINSSLSRR PRISECVEEE EEDGGGFDLF EEMRQPIQEN
     IPMIILEEEE DDNDNLVMSV ARPVRVHFAV DVENLHAHQS VYVVGSNDVL GTWEATRAMP
     LVQDPDRFMR WKGSIVTDVH QLKFRYFIGY NLMSDQGERL IVDKWEAFLH PRSTLCLAES
     RNDECRVDRV DLFGYYAGRK CVSDGWLQYP DENQILLRLH GNALKFYKTA KERKNCRVKM
     TPLDVRFKAP PSGHISFSYG EDEEDEEEDQ NVPSNKCTHS ATHVAVLSDP RPKFYDQEDT
     GVTFNNNKDY LVFRTHCLAA EFLAFYIEIF SEERKRIGAC YALPSSLQDA SGIIHLPFIN
     SSGRPIGQVS IEYLCVRALT RLDGPQFMDQ TYCRHWKKRN ALEVGHRGAG NSYTKFAMAR
     ENTIHSLNTA AKNGADYVEF DVQLTKDRIA VIYHDFHVLV SVARRDGLAM PPPMTREQLD
     SSNLDYHELP VKDLKLSQLK LLMLDHLSFP QKKENVKKLV EAGEEEEDFK PFPTLLEALT
     KVDPDVGFNV EVKYPMMQNN GEHECDHYFE RNLFVDVILA DVMKHAGNRR IMFSSFDPDI
     CSMVATKQNK YPVLFLCVGE TQRYTPFQDQ RTSTSMTAVN FAAGADLLGV NFNSEDLLKD
     PMPVKKANEF GMVTFVWGED LDKKENINYF KKELGVDGVI YDRIGEEERR RNVFIVEREQ
     KRALLSCSGA STPQRAASPS PVSSENNNTS PPHSAKLTRN AQSDSALLEE NEDDVEHLSD
     KLNITGFQSA PMVSTK