GPTC4_BOVIN
ID GPTC4_BOVIN Reviewed; 408 AA.
AC Q2KJE1;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 07-MAR-2006, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=G patch domain-containing protein 4;
GN Name=GPATCH4; Synonyms=GPATC4;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Thymus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; BC105388; AAI05389.1; -; mRNA.
DR RefSeq; NP_001071597.1; NM_001078129.2.
DR AlphaFoldDB; Q2KJE1; -.
DR STRING; 9913.ENSBTAP00000033817; -.
DR PaxDb; Q2KJE1; -.
DR Ensembl; ENSBTAT00000033914; ENSBTAP00000033817; ENSBTAG00000000406.
DR GeneID; 768314; -.
DR KEGG; bta:768314; -.
DR CTD; 54865; -.
DR VEuPathDB; HostDB:ENSBTAG00000000406; -.
DR VGNC; VGNC:29519; GPATCH4.
DR eggNOG; KOG2809; Eukaryota.
DR GeneTree; ENSGT00390000008765; -.
DR HOGENOM; CLU_674312_0_0_1; -.
DR InParanoid; Q2KJE1; -.
DR OrthoDB; 1573336at2759; -.
DR TreeFam; TF326721; -.
DR Proteomes; UP000009136; Chromosome 3.
DR Bgee; ENSBTAG00000000406; Expressed in prostate gland and 105 other tissues.
DR ExpressionAtlas; Q2KJE1; baseline.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0090069; P:regulation of ribosome biogenesis; IBA:GO_Central.
DR InterPro; IPR000467; G_patch_dom.
DR Pfam; PF01585; G-patch; 1.
DR SMART; SM00443; G_patch; 1.
DR PROSITE; PS50174; G_PATCH; 1.
PE 2: Evidence at transcript level;
KW Acetylation; Isopeptide bond; Phosphoprotein; Reference proteome;
KW Ubl conjugation.
FT CHAIN 1..408
FT /note="G patch domain-containing protein 4"
FT /id="PRO_0000287461"
FT DOMAIN 11..57
FT /note="G-patch"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT REGION 116..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 187..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..134
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..236
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..280
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..342
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 355..370
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 1
FT /note="N-acetylmethionine"
FT /evidence="ECO:0000250|UniProtKB:Q5T3I0"
FT MOD_RES 4
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q5T3I0"
FT MOD_RES 116
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q5T3I0"
FT MOD_RES 128
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q5T3I0"
FT MOD_RES 130
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q5T3I0"
FT CROSSLNK 46
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q5T3I0"
SQ SEQUENCE 408 AA; 46797 MW; D6BADE93468B83C1 CRC64;
MSITPEVKSR GMKFAEEQLL KHGWTQGKGL GRKENGITQA LRVTLKQDTY GVGHDPAKEF
TNHWWNDLFN KTAANLVVET RQDGVQIRRL SKETTRQDHA KPNLLYQKFV KTATLTSSGE
KPDKDWESCS DDDSQEPKPP NVLTDEMLLQ ACEGRTAHKA ARLGITMKAK LARLEAQEQA
FLAQLKGQDP GVPQLQSESK SPKKKKKKRK QKEEEEPTTT ERSAEKYSEH TDESIRKSKK
KKRQHQEERV TDEREGTAIE NEEETIRTGG LGELKNREHV DRSFRKKKRR GQHHEERAEL
AVLDNEGGKV AVSEVGTEEA ERRVYTHPCG RSKKRRQHEE EDLNTEDEEV EEALVDSGTR
EAESRSCSDQ KRGRSKKKRR QYQEEEVLDG PGVNTAQKAK KKKQKKRD