ID   GPTC4_RAT               Reviewed;         407 AA.
AC   Q566R3;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=G patch domain-containing protein 4;
GN   Name=Gpatch4; Synonyms=Gpatc4;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Thymus;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; BC093381; AAH93381.1; -; mRNA.
DR   RefSeq; NP_001020150.1; NM_001024979.1.
DR   RefSeq; XP_008759351.1; XM_008761129.1.
DR   RefSeq; XP_008759352.1; XM_008761130.2.
DR   RefSeq; XP_008759353.1; XM_008761131.2.
DR   RefSeq; XP_008759354.1; XM_008761132.2.
DR   AlphaFoldDB; Q566R3; -.
DR   STRING; 10116.ENSRNOP00000053762; -.
DR   iPTMnet; Q566R3; -.
DR   PhosphoSitePlus; Q566R3; -.
DR   PaxDb; Q566R3; -.
DR   Ensembl; ENSRNOT00000056923; ENSRNOP00000053762; ENSRNOG00000018969.
DR   GeneID; 295228; -.
DR   KEGG; rno:295228; -.
DR   UCSC; RGD:1311086; rat.
DR   CTD; 54865; -.
DR   RGD; 1311086; Gpatch4.
DR   eggNOG; KOG2809; Eukaryota.
DR   GeneTree; ENSGT00390000008765; -.
DR   HOGENOM; CLU_674312_0_0_1; -.
DR   InParanoid; Q566R3; -.
DR   OMA; ILGKYGW; -.
DR   OrthoDB; 1573336at2759; -.
DR   PhylomeDB; Q566R3; -.
DR   TreeFam; TF326721; -.
DR   PRO; PR:Q566R3; -.
DR   Proteomes; UP000002494; Chromosome 2.
DR   Bgee; ENSRNOG00000018969; Expressed in ovary and 19 other tissues.
DR   Genevisible; Q566R3; RN.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; ISO:RGD.
DR   GO; GO:0090069; P:regulation of ribosome biogenesis; IBA:GO_Central.
DR   InterPro; IPR000467; G_patch_dom.
DR   Pfam; PF01585; G-patch; 1.
DR   SMART; SM00443; G_patch; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Isopeptide bond; Phosphoprotein; Reference proteome;
KW   Ubl conjugation.
FT   CHAIN           1..407
FT                   /note="G patch domain-containing protein 4"
FT                   /id="PRO_0000287464"
FT   DOMAIN          11..57
FT                   /note="G-patch"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT   REGION          116..138
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          187..407
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        117..138
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        201..236
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        362..394
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:Q5T3I0"
FT   MOD_RES         4
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q5T3I0"
FT   MOD_RES         116
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q5T3I0"
FT   MOD_RES         128
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q5T3I0"
FT   MOD_RES         130
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q5T3I0"
FT   MOD_RES         258
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q3TFK5"
FT   CROSSLNK        46
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q5T3I0"
SQ   SEQUENCE   407 AA;  46073 MW;  7A2C233451EAA800 CRC64;
     MSVTPEVKSR GMKFAEEQLL KHGWTQGKGL GRKENGITQA LKVTLKQDTH GVGHDPAKEF
     TDHWWSDLFN KTAANLVVDS GKDGVQIRRL SKETTQRSHS KPSLLYQKFV KTATLTSGEE
     KPDRDLESCS DVDNREPIPP KILTDEMLLK ACEGRTAHKA ARIGITMKAK LARLEAQEQA
     FLARLKGSKD VGTSQPLTDS EPSQKKKKRR KQKEEEEAAT TEKSLGEELL EHTDKSFRKS
     KKKKKKKKDE REGTAIGSEE EEAAGVCGPA ELSTEQSDQS SRKKKKRRRR HHEEEEEMGV
     CDEGGRDVTG GPKAVNSGAD TDPWRSSKKR QTCEEDLDTQ DEEDKDDLTK KERKVRKKDK
     KKRQQYCEEV LDVSNKDDGR TWEAEDGGER SQPHPKARAK KKKRKTD