ID   GRA1_NEOCA              Reviewed;         217 AA.
AC   P90661; O02507; Q25539;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Dense granule protein 1;
DE   AltName: Full=Antigen Nc4.1;
DE   AltName: Full=NcDG1;
DE   Flags: Precursor;
GN   Name=DG1;
OS   Neospora caninum (Coccidian parasite).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Sarcocystidae; Neospora.
OX   NCBI_TaxID=29176;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Nc-1;
RX   PubMed=9247937; DOI=10.1016/s0166-6851(97)00070-4;
RA   Lally N.C., Jenkins M.C., Liddell S., Dubey J.P.;
RT   "A dense granule protein (NCDG1) gene from Neospora caninum.";
RL   Mol. Biochem. Parasitol. 87:239-243(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 15-217.
RC   STRAIN=Nc-1;
RX   PubMed=8705668; DOI=10.1128/cdli.3.3.275-279.1996;
RA   Lally N.C., Jenkins M.C., Dubey J.P.;
RT   "Evaluation of two Neospora caninum recombinant antigens for use in an
RT   enzyme-linked immunosorbent assay for the diagnosis of bovine
RT   neosporosis.";
RL   Clin. Diagn. Lab. Immunol. 3:275-279(1996).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the Gra7 family. {ECO:0000305}.
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DR   EMBL; U72991; AAB48402.1; -; mRNA.
DR   EMBL; U82229; AAC47661.1; -; mRNA.
DR   EMBL; U36386; AAC47096.1; -; mRNA.
DR   AlphaFoldDB; P90661; -.
DR   VEuPathDB; ToxoDB:Ncaninum_LIV_000658800; -.
DR   VEuPathDB; ToxoDB:NCLIV_021640; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008120; Dense_granule_Gra7_protein.
DR   PRINTS; PR01747; DENSEGRNULE7.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Secreted; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..217
FT                   /note="Dense granule protein 1"
FT                   /id="PRO_0000021364"
FT   REGION          171..217
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        173..196
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        191
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        15..18
FT                   /note="GLAI -> IRHE (in Ref. 2)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   217 AA;  22495 MW;  098B4C1B33705CC2 CRC64;
     MARQATFIVA LCVCGLAIAG LPRLASAGDL ATEQHEGDIG YGVRAYAGVS NYDGDDDAAG
     NPVDSDVTDD AITDGEWPRV VSGQKPHTTQ KGSLIKKLAV PVVGALTSYL VADRVLPELT
     SAEEEGTESI PGKKRVKTAV GIAALVAAAA FAGLGLARTF RHFVPKKSKT VASEDSALGN
     SEEQYVEGTV NGSSDPEQER AGGPLIPEGD EQEVDTE