ID   GRA1_TOXGO              Reviewed;         190 AA.
AC   P13403;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Dense granule protein 1;
DE            Short=Protein GRA 1;
DE   AltName: Full=Major antigen p24;
DE   Flags: Precursor;
GN   Name=GRA1;
OS   Toxoplasma gondii.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX   NCBI_TaxID=5811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2798425; DOI=10.1073/pnas.86.19.7537;
RA   Cesbron-Delauw M.-F., Guy B., Torpier G., Pierce R.J., Lenzen G.,
RA   Cesbron J.Y., Charif H., Lepage P., Darcy F., Lecocq J.-P., Capron A.;
RT   "Molecular characterization of a 23-kilodalton major antigen secreted by
RT   Toxoplasma gondii.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:7537-7541(1989).
CC   -!- SUBCELLULAR LOCATION: Secreted. Note=Located in dense granules of
CC       tachyzoites.
CC   -!- CAUTION: PubMed:2798425 reported that there are two potential EF-hand
CC       regions, but the evidence seems weak. {ECO:0000305}.
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DR   EMBL; M26007; AAA30141.1; -; Genomic_DNA.
DR   PIR; A33839; A33839.
DR   AlphaFoldDB; P13403; -.
DR   SMR; P13403; -.
DR   VEuPathDB; ToxoDB:TGARI_270250; -.
DR   VEuPathDB; ToxoDB:TGCAST_270250; -.
DR   VEuPathDB; ToxoDB:TGCOUG_270250; -.
DR   VEuPathDB; ToxoDB:TGDOM2_270250; -.
DR   VEuPathDB; ToxoDB:TGFOU_270250; -.
DR   VEuPathDB; ToxoDB:TGGT1_270250; -.
DR   VEuPathDB; ToxoDB:TGMAS_270250; -.
DR   VEuPathDB; ToxoDB:TGME49_270250; -.
DR   VEuPathDB; ToxoDB:TGP89_270250; -.
DR   VEuPathDB; ToxoDB:TGPRC2_270250; -.
DR   VEuPathDB; ToxoDB:TGRH88_081130; -.
DR   VEuPathDB; ToxoDB:TGRUB_270250; -.
DR   VEuPathDB; ToxoDB:TGVAND_270250; -.
DR   VEuPathDB; ToxoDB:TGVEG_270250; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Glycoprotein; Secreted; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..190
FT                   /note="Dense granule protein 1"
FT                   /id="PRO_0000021365"
FT   CARBOHYD        30
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   190 AA;  20149 MW;  3B05D2610C615A53 CRC64;
     MVRVSAIVGA AASVFVCLSA GAYAAEGGDN QSSAVSDRAS LFGLLSGGTG QGLGIGESVD
     LEMMGNTYRV ERPTGNPDLL KIAIKASDGS YSEVGNVNVE EVIDTMKSMQ RDEDIFLRAL
     NKGETVEEAI EDVAQAEGLN SEQTLQLEDA VSAVASVVQD EMKVIDDVQQ LEKDKQQLKD
     DIGFLTGERE