ID   GRA2A_POGPU             Reviewed;          13 AA.
AC   P69843;
DT   24-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 27.
DE   RecName: Full=Grammistin Pp 2a;
OS   Pogonoperca punctata (Clown grouper) (Grammistes punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Serranoidei; Serranidae; Epinephelinae;
OC   Grammistini; Pogonoperca.
OX   NCBI_TaxID=160738;
RN   [1]
RP   PROTEIN SEQUENCE, AND MASS SPECTROMETRY.
RC   TISSUE=Skin secretion;
RX   DOI=10.1046/j.1444-2906.2001.00213.x;
RA   Shiomi K., Yokota H., Nagashima Y., Ishida M.;
RT   "Primary and secondary structures of grammistins, peptide toxins isolated
RT   from the skin secretion of the soapfish Pogonoperca punctata.";
RL   Fish. Sci. 67:163-169(2001).
CC   -!- FUNCTION: Has lytic, hemolytic and antibacterial activities.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the skin glands.
CC   -!- MASS SPECTROMETRY: Mass=1547; Method=MALDI;
CC       Evidence={ECO:0000269|Ref.1};
CC   -!- SIMILARITY: Belongs to the grammistin family. Group 2 subfamily.
CC       {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0044179; P:hemolysis in another organism; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Cytolysis; Direct protein sequencing; Hemolysis;
KW   Secreted.
FT   PEPTIDE         1..13
FT                   /note="Grammistin Pp 2a"
FT                   /id="PRO_0000044526"
SQ   SEQUENCE   13 AA;  1449 MW;  1EBDEFF24B8935B0 CRC64;
     FIGGIISLIK KLF