ID   GRAB_GRASX              Reviewed;          12 AA.
AC   P69839;
DT   24-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   11-DEC-2019, entry version 21.
DE   RecName: Full=Grammistin Gs B;
OS   Grammistes sexlineatus (Goldenstriped soapfish) (Perca sexlineata).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Serranoidei; Serranidae; Epinephelinae;
OC   Grammistini; Grammistes.
OX   NCBI_TaxID=270576;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Skin secretion;
RX   PubMed=15777955; DOI=10.1016/j.toxicon.2004.12.021;
RA   Sugiyama N., Araki M., Ishida M., Nagashima Y., Shiomi K.;
RT   "Further isolation and characterization of grammistins from the skin
RT   secretion of the soapfish Grammistes sexlineatus.";
RL   Toxicon 45:595-601(2005).
CC   -!- FUNCTION: Has lytic activity, but has no substantial hemolytic
CC       activity. Has antibacterial activity with a broad spectrum against
CC       various species of bacteria including both Gram-positive and Gram-
CC       negative groups.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the skin glands.
CC   -!- SIMILARITY: Belongs to the grammistin family. Group 2 subfamily.
CC       {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Cytolysis; Direct protein sequencing; Secreted.
FT   PEPTIDE         1..12
FT                   /note="Grammistin Gs B"
FT                   /id="PRO_0000044522"
SQ   SEQUENCE   12 AA;  1398 MW;  1EBDF8C214C9D5B0 CRC64;
     IGGIISFFKR LF