GRCA_ECOHS
ID GRCA_ECOHS Reviewed; 127 AA.
AC A8A391;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 1.
DT 25-MAY-2022, entry version 71.
DE RecName: Full=Autonomous glycyl radical cofactor {ECO:0000255|HAMAP-Rule:MF_00806};
GN Name=grcA {ECO:0000255|HAMAP-Rule:MF_00806}; OrderedLocusNames=EcHS_A2736;
OS Escherichia coli O9:H4 (strain HS).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=331112;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HS;
RX PubMed=18676672; DOI=10.1128/jb.00619-08;
RA Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F.,
RA Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R.,
RA Henderson I.R., Sperandio V., Ravel J.;
RT "The pangenome structure of Escherichia coli: comparative genomic analysis
RT of E. coli commensal and pathogenic isolates.";
RL J. Bacteriol. 190:6881-6893(2008).
CC -!- FUNCTION: Acts as a radical domain for damaged PFL and possibly other
CC radical proteins. {ECO:0000255|HAMAP-Rule:MF_00806}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000802; ABV06995.1; -; Genomic_DNA.
DR RefSeq; WP_000627807.1; NC_009800.1.
DR AlphaFoldDB; A8A391; -.
DR SMR; A8A391; -.
DR GeneID; 66673531; -.
DR KEGG; ecx:EcHS_A2736; -.
DR HOGENOM; CLU_133780_0_0_6; -.
DR OMA; LGQFEYR; -.
DR Proteomes; UP000001123; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR HAMAP; MF_00806; GrcA; 1.
DR InterPro; IPR019777; Form_AcTrfase_GR_CS.
DR InterPro; IPR001150; Gly_radical.
DR InterPro; IPR011140; Glycyl_radical_cofactor_GrcA.
DR Pfam; PF01228; Gly_radical; 1.
DR PIRSF; PIRSF000378; Gly_radicl_yfiD; 1.
DR TIGRFAMs; TIGR04365; spare_glycyl; 1.
DR PROSITE; PS00850; GLY_RADICAL_1; 1.
DR PROSITE; PS51149; GLY_RADICAL_2; 1.
PE 3: Inferred from homology;
KW Acetylation; Organic radical.
FT CHAIN 1..127
FT /note="Autonomous glycyl radical cofactor"
FT /id="PRO_1000083717"
FT DOMAIN 5..127
FT /note="Glycine radical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
FT MOD_RES 48
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
FT MOD_RES 88
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
FT MOD_RES 92
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
FT MOD_RES 102
FT /note="Glycine radical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
SQ SEQUENCE 127 AA; 14284 MW; 6BA617E67D6540CE CRC64;
MITGIQITKA ANDDLLNSFW LLDSEKGEAR CIVAKAGYAE DEVVAVSKLG DIEYREVPVE
VKPEVRVEGG QHLNVNVLRR ETLEDAVKHP EKYPQLTIRV SGYAVRFNSL TPEQQRDVIA
RTFTESL