GRCA_ESCF3
ID GRCA_ESCF3 Reviewed; 127 AA.
AC B7LUY6;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=Autonomous glycyl radical cofactor {ECO:0000255|HAMAP-Rule:MF_00806};
GN Name=grcA {ECO:0000255|HAMAP-Rule:MF_00806}; OrderedLocusNames=EFER_0495;
OS Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM
OS 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=585054;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35469 / DSM 13698 / BCRC 15582 / CCUG 18766 / IAM 14443 / JCM
RC 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73;
RX PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT "Organised genome dynamics in the Escherichia coli species results in
RT highly diverse adaptive paths.";
RL PLoS Genet. 5:E1000344-E1000344(2009).
CC -!- FUNCTION: Acts as a radical domain for damaged PFL and possibly other
CC radical proteins. {ECO:0000255|HAMAP-Rule:MF_00806}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU928158; CAQ88044.1; -; Genomic_DNA.
DR RefSeq; WP_000627804.1; NC_011740.1.
DR AlphaFoldDB; B7LUY6; -.
DR SMR; B7LUY6; -.
DR EnsemblBacteria; CAQ88044; CAQ88044; EFER_0495.
DR GeneID; 60903721; -.
DR GeneID; 67416959; -.
DR KEGG; efe:EFER_0495; -.
DR HOGENOM; CLU_133780_0_0_6; -.
DR OMA; LGQFEYR; -.
DR OrthoDB; 116406at2; -.
DR BioCyc; EFER585054:EFER_RS02610-MON; -.
DR Proteomes; UP000000745; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR HAMAP; MF_00806; GrcA; 1.
DR InterPro; IPR019777; Form_AcTrfase_GR_CS.
DR InterPro; IPR001150; Gly_radical.
DR InterPro; IPR011140; Glycyl_radical_cofactor_GrcA.
DR Pfam; PF01228; Gly_radical; 1.
DR PIRSF; PIRSF000378; Gly_radicl_yfiD; 1.
DR TIGRFAMs; TIGR04365; spare_glycyl; 1.
DR PROSITE; PS00850; GLY_RADICAL_1; 1.
DR PROSITE; PS51149; GLY_RADICAL_2; 1.
PE 3: Inferred from homology;
KW Acetylation; Organic radical.
FT CHAIN 1..127
FT /note="Autonomous glycyl radical cofactor"
FT /id="PRO_1000133990"
FT DOMAIN 5..127
FT /note="Glycine radical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
FT MOD_RES 48
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
FT MOD_RES 88
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
FT MOD_RES 92
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
FT MOD_RES 102
FT /note="Glycine radical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
SQ SEQUENCE 127 AA; 14268 MW; 6BB8F8F88C8A5E21 CRC64;
MITGIQITKA ANDDLLNSFW LLDSEKGEAR CIVAKAGFAE DEVVAVSKLG DIEYREVPVE
VKPEVRVEGG QHLNVNVLRR ETLEDAVKHP EKYPQLTIRV SGYAVRFNSL TPEQQRDVIA
RTFTESL