ID   GRCA_HAEI8              Reviewed;         127 AA.
AC   Q4QPM7;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Autonomous glycyl radical cofactor {ECO:0000255|HAMAP-Rule:MF_00806};
GN   Name=grcA {ECO:0000255|HAMAP-Rule:MF_00806}; OrderedLocusNames=NTHI0022;
OS   Haemophilus influenzae (strain 86-028NP).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=281310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=86-028NP;
RX   PubMed=15968074; DOI=10.1128/jb.187.13.4627-4636.2005;
RA   Harrison A., Dyer D.W., Gillaspy A., Ray W.C., Mungur R., Carson M.B.,
RA   Zhong H., Gipson J., Gipson M., Johnson L.S., Lewis L., Bakaletz L.O.,
RA   Munson R.S. Jr.;
RT   "Genomic sequence of an otitis media isolate of nontypeable Haemophilus
RT   influenzae: comparative study with H. influenzae serotype d, strain KW20.";
RL   J. Bacteriol. 187:4627-4636(2005).
CC   -!- FUNCTION: Acts as a radical domain for damaged PFL and possibly other
CC       radical proteins. {ECO:0000255|HAMAP-Rule:MF_00806}.
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DR   EMBL; CP000057; AAX87020.1; -; Genomic_DNA.
DR   RefSeq; WP_005687457.1; NC_007146.2.
DR   AlphaFoldDB; Q4QPM7; -.
DR   SMR; Q4QPM7; -.
DR   EnsemblBacteria; AAX87020; AAX87020; NTHI0022.
DR   KEGG; hit:NTHI0022; -.
DR   HOGENOM; CLU_133780_0_0_6; -.
DR   OMA; LGQFEYR; -.
DR   OrthoDB; 116406at2; -.
DR   Proteomes; UP000002525; Chromosome.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   HAMAP; MF_00806; GrcA; 1.
DR   InterPro; IPR019777; Form_AcTrfase_GR_CS.
DR   InterPro; IPR001150; Gly_radical.
DR   InterPro; IPR011140; Glycyl_radical_cofactor_GrcA.
DR   Pfam; PF01228; Gly_radical; 1.
DR   PIRSF; PIRSF000378; Gly_radicl_yfiD; 1.
DR   TIGRFAMs; TIGR04365; spare_glycyl; 1.
DR   PROSITE; PS00850; GLY_RADICAL_1; 1.
DR   PROSITE; PS51149; GLY_RADICAL_2; 1.
PE   3: Inferred from homology;
KW   Organic radical.
FT   CHAIN           1..127
FT                   /note="Autonomous glycyl radical cofactor"
FT                   /id="PRO_1000083723"
FT   DOMAIN          5..127
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
FT   MOD_RES         102
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
SQ   SEQUENCE   127 AA;  14319 MW;  3283882DAA993504 CRC64;
     MIKGIQITQA ANDNLLNSFW LLDSEKNEVR CLCAKGEFAE DQVVAVSELG QIEYRELPVN
     VAPTVKVEGG QHLNVNVLRR ETLEDAVNNP DKYPQLTIRV SGYAVRFNSL TPEQQRDVIT
     RTFTESL