ID   GRCA_PHOPR              Reviewed;         125 AA.
AC   Q6LUP6;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 2.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Autonomous glycyl radical cofactor {ECO:0000255|HAMAP-Rule:MF_00806};
GN   Name=grcA {ECO:0000255|HAMAP-Rule:MF_00806}; OrderedLocusNames=PBPRA0556;
OS   Photobacterium profundum (strain SS9).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Photobacterium.
OX   NCBI_TaxID=298386;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1253 / SS9;
RX   PubMed=15746425; DOI=10.1126/science.1103341;
RA   Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M.,
RA   Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C.,
RA   Bartlett D.H., Valle G.;
RT   "Life at depth: Photobacterium profundum genome sequence and expression
RT   analysis.";
RL   Science 307:1459-1461(2005).
CC   -!- FUNCTION: Acts as a radical domain for damaged PFL and possibly other
CC       radical proteins. {ECO:0000255|HAMAP-Rule:MF_00806}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAG18979.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CR378664; CAG18979.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_011217330.1; NC_006370.1.
DR   AlphaFoldDB; Q6LUP6; -.
DR   SMR; Q6LUP6; -.
DR   STRING; 298386.PBPRA0556; -.
DR   EnsemblBacteria; CAG18979; CAG18979; PBPRA0556.
DR   KEGG; ppr:PBPRA0556; -.
DR   eggNOG; COG3445; Bacteria.
DR   HOGENOM; CLU_133780_0_0_6; -.
DR   OrthoDB; 116406at2; -.
DR   Proteomes; UP000000593; Chromosome 1.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   HAMAP; MF_00806; GrcA; 1.
DR   InterPro; IPR019777; Form_AcTrfase_GR_CS.
DR   InterPro; IPR001150; Gly_radical.
DR   InterPro; IPR011140; Glycyl_radical_cofactor_GrcA.
DR   Pfam; PF01228; Gly_radical; 1.
DR   PIRSF; PIRSF000378; Gly_radicl_yfiD; 1.
DR   TIGRFAMs; TIGR04365; spare_glycyl; 1.
DR   PROSITE; PS00850; GLY_RADICAL_1; 1.
DR   PROSITE; PS51149; GLY_RADICAL_2; 1.
PE   3: Inferred from homology;
KW   Organic radical; Reference proteome.
FT   CHAIN           1..125
FT                   /note="Autonomous glycyl radical cofactor"
FT                   /id="PRO_0000166705"
FT   DOMAIN          5..125
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
FT   MOD_RES         100
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
SQ   SEQUENCE   125 AA;  13749 MW;  E5D9E37893A66E9E CRC64;
     MITGIQITKS ANDDLLNSIW LLDSETNEAR CVVAKAGFEE DQVIAAADLG EYESRDVAIE
     VPAKVEGGQH LNVNVLKKET LEDAVAHPEK YPQLTIRVSG YAVRFNSLTT EQQKDVIART
     FTSSL