ID   GRCA_SERLI              Reviewed;         127 AA.
AC   P18953;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 2.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Autonomous glycyl radical cofactor {ECO:0000255|HAMAP-Rule:MF_00806};
GN   Name=grcA {ECO:0000255|HAMAP-Rule:MF_00806};
OS   Serratia liquefaciens.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Serratia.
OX   NCBI_TaxID=614;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1640837; DOI=10.1111/j.1365-2958.1992.tb00857.x;
RA   Givskov M., Molin S.;
RT   "Expression of extracellular phospholipase from Serratia liquefaciens is
RT   growth-phase-dependent, catabolite-repressed and regulated by
RT   anaerobiosis.";
RL   Mol. Microbiol. 6:1363-1374(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 21-127.
RX   PubMed=3056919; DOI=10.1128/jb.170.12.5855-5862.1988;
RA   Givskov M., Olsen L., Molin S.;
RT   "Cloning and expression in Escherichia coli of the gene for extracellular
RT   phospholipase A1 from Serratia liquefaciens.";
RL   J. Bacteriol. 170:5855-5862(1988).
CC   -!- FUNCTION: Acts as a radical domain for damaged PFL and possibly other
CC       radical proteins. {ECO:0000255|HAMAP-Rule:MF_00806}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X66505; CAA47136.1; -; Genomic_DNA.
DR   EMBL; M23640; -; NOT_ANNOTATED_CDS; mRNA.
DR   PIR; S22666; S22666.
DR   AlphaFoldDB; P18953; -.
DR   SMR; P18953; -.
DR   STRING; 614.XJ20_04310; -.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   HAMAP; MF_00806; GrcA; 1.
DR   InterPro; IPR019777; Form_AcTrfase_GR_CS.
DR   InterPro; IPR001150; Gly_radical.
DR   InterPro; IPR011140; Glycyl_radical_cofactor_GrcA.
DR   Pfam; PF01228; Gly_radical; 1.
DR   PIRSF; PIRSF000378; Gly_radicl_yfiD; 1.
DR   TIGRFAMs; TIGR04365; spare_glycyl; 1.
DR   PROSITE; PS00850; GLY_RADICAL_1; 1.
DR   PROSITE; PS51149; GLY_RADICAL_2; 1.
PE   2: Evidence at transcript level;
KW   Organic radical.
FT   CHAIN           1..127
FT                   /note="Autonomous glycyl radical cofactor"
FT                   /id="PRO_0000166709"
FT   DOMAIN          5..127
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
FT   MOD_RES         102
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
FT   CONFLICT        29..35
FT                   /note="ARCVCAN -> VVRMRQ (in Ref. 2; M23640)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   127 AA;  14375 MW;  AE5769D3F5A76DCF CRC64;
     MITGIQITKA NDQALVNSFW LLDDEKAEAR CVCANGQYAE DQVVAVSDLG QIEYREVPLE
     MQPTVRVEGG QHLNVNVLRR ETLEDAVKHP EKYPQLTIRV SGYAVRFNSL TPEQQRDVIA
     RTFTESL