ID   GRCA_VIBCM              Reviewed;         125 AA.
AC   C3LQD3;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Autonomous glycyl radical cofactor {ECO:0000255|HAMAP-Rule:MF_00806};
GN   Name=grcA {ECO:0000255|HAMAP-Rule:MF_00806}; OrderedLocusNames=VCM66_2284;
OS   Vibrio cholerae serotype O1 (strain M66-2).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=579112;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M66-2;
RX   PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA   Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA   Wang W., Wang J., Qian W., Li D., Wang L.;
RT   "A recalibrated molecular clock and independent origins for the cholera
RT   pandemic clones.";
RL   PLoS ONE 3:E4053-E4053(2008).
CC   -!- FUNCTION: Acts as a radical domain for damaged PFL and possibly other
CC       radical proteins. {ECO:0000255|HAMAP-Rule:MF_00806}.
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DR   EMBL; CP001233; ACP06585.1; -; Genomic_DNA.
DR   RefSeq; WP_000614136.1; NC_012578.1.
DR   AlphaFoldDB; C3LQD3; -.
DR   SMR; C3LQD3; -.
DR   PRIDE; C3LQD3; -.
DR   EnsemblBacteria; ACP06585; ACP06585; VCM66_2284.
DR   GeneID; 57740971; -.
DR   GeneID; 57990753; -.
DR   GeneID; 66939802; -.
DR   KEGG; vcm:VCM66_2284; -.
DR   HOGENOM; CLU_133780_0_0_6; -.
DR   OMA; LGQFEYR; -.
DR   Proteomes; UP000001217; Chromosome I.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   HAMAP; MF_00806; GrcA; 1.
DR   InterPro; IPR019777; Form_AcTrfase_GR_CS.
DR   InterPro; IPR001150; Gly_radical.
DR   InterPro; IPR011140; Glycyl_radical_cofactor_GrcA.
DR   Pfam; PF01228; Gly_radical; 1.
DR   PIRSF; PIRSF000378; Gly_radicl_yfiD; 1.
DR   TIGRFAMs; TIGR04365; spare_glycyl; 1.
DR   PROSITE; PS00850; GLY_RADICAL_1; 1.
DR   PROSITE; PS51149; GLY_RADICAL_2; 1.
PE   3: Inferred from homology;
KW   Organic radical.
FT   CHAIN           1..125
FT                   /note="Autonomous glycyl radical cofactor"
FT                   /id="PRO_1000148572"
FT   DOMAIN          5..125
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
FT   MOD_RES         100
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
SQ   SEQUENCE   125 AA;  13910 MW;  9E1B491FE0D9C814 CRC64;
     MIQGIQITKA ANDDLLNSIW LLDSEKNEAR CVAALKGFEA DQVVSINDLG QFESREVAIE
     AAPRIEGGQH LNVNVLKRET LEDAVAHPEK YPQLTIRVSG YAVRFNSLTA EQQRDVIART
     FTESL