ID   GRDP1_ARATH             Reviewed;         819 AA.
AC   Q9ZQ47; F4IJL4;
DT   29-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Glycine-rich domain-containing protein 1 {ECO:0000303|Ref.4};
DE            Short=AtGRDP1 {ECO:0000303|Ref.4};
GN   Name=GRDP1 {ECO:0000303|Ref.4};
GN   OrderedLocusNames=At2g22660 {ECO:0000312|Araport:AT2G22660};
GN   ORFNames=T9I22.10 {ECO:0000312|EMBL:AAD15574.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   FUNCTION, DISRUPTION PHENOTYPE, AND INDUCTION.
RC   STRAIN=cv. Columbia;
RX   DOI=10.1007/s11105-014-0714-4;
RA   Rodriguez-Hernandez A.A., Ortega-Amaro M.A., Delgado-Sanchez P.,
RA   Salinas J., Jimenez-Bremont J.F.;
RT   "AtGRDP1 gene encoding a glycine-rich domain protein is involved in
RT   germination and responds to ABA signalling.";
RL   Plant Mol. Biol. Rep. 32:1187-1202(2014).
CC   -!- FUNCTION: Plays a regulatory role in abscisic acid (ABA) signaling and
CC       tolerance to abiotic stress during germination. May be involved in the
CC       regulation of the ABI transcriptional factors. {ECO:0000269|Ref.4}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q9ZQ47-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q9ZQ47-2; Sequence=VSP_057611, VSP_057612;
CC   -!- INDUCTION: Up-regulated upon salt, osmotic, glucose or exogenous
CC       abscisic acid treatment. {ECO:0000269|Ref.4}.
CC   -!- DISRUPTION PHENOTYPE: Increased sensitivity to salt and osmotic stress
CC       in germination and cotyledon development. Abscisic acid
CC       hypersensitivity. {ECO:0000269|Ref.4}.
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DR   EMBL; AC006340; AAD15574.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC07334.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC07335.1; -; Genomic_DNA.
DR   EMBL; AY070719; -; NOT_ANNOTATED_CDS; mRNA.
DR   PIR; C84615; C84615.
DR   RefSeq; NP_001031396.1; NM_001036319.2. [Q9ZQ47-1]
DR   RefSeq; NP_179851.2; NM_127831.3. [Q9ZQ47-2]
DR   AlphaFoldDB; Q9ZQ47; -.
DR   SMR; Q9ZQ47; -.
DR   STRING; 3702.AT2G22660.2; -.
DR   SwissPalm; Q9ZQ47; -.
DR   PaxDb; Q9ZQ47; -.
DR   PRIDE; Q9ZQ47; -.
DR   ProteomicsDB; 220596; -. [Q9ZQ47-1]
DR   EnsemblPlants; AT2G22660.1; AT2G22660.1; AT2G22660. [Q9ZQ47-2]
DR   EnsemblPlants; AT2G22660.2; AT2G22660.2; AT2G22660. [Q9ZQ47-1]
DR   GeneID; 816797; -.
DR   Gramene; AT2G22660.1; AT2G22660.1; AT2G22660. [Q9ZQ47-2]
DR   Gramene; AT2G22660.2; AT2G22660.2; AT2G22660. [Q9ZQ47-1]
DR   KEGG; ath:AT2G22660; -.
DR   Araport; AT2G22660; -.
DR   TAIR; locus:2065983; AT2G22660.
DR   eggNOG; ENOG502QRQZ; Eukaryota.
DR   HOGENOM; CLU_011059_0_0_1; -.
DR   InParanoid; Q9ZQ47; -.
DR   OMA; RFLYEGP; -.
DR   OrthoDB; 246640at2759; -.
DR   PhylomeDB; Q9ZQ47; -.
DR   PRO; PR:Q9ZQ47; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q9ZQ47; baseline and differential.
DR   Genevisible; Q9ZQ47; AT.
DR   GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR   GO; GO:0009738; P:abscisic acid-activated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0071470; P:cellular response to osmotic stress; IMP:UniProtKB.
DR   GO; GO:0009787; P:regulation of abscisic acid-activated signaling pathway; IMP:UniProtKB.
DR   InterPro; IPR009836; GRDP-like.
DR   PANTHER; PTHR34365; PTHR34365; 1.
DR   Pfam; PF07173; GRDP-like; 2.
PE   2: Evidence at transcript level;
KW   Abscisic acid signaling pathway; Alternative splicing; Reference proteome;
KW   Stress response.
FT   CHAIN           1..819
FT                   /note="Glycine-rich domain-containing protein 1"
FT                   /id="PRO_0000432852"
FT   VAR_SEQ         580..586
FT                   /note="KIFSGRK -> YSTILFQ (in isoform 2)"
FT                   /id="VSP_057611"
FT   VAR_SEQ         587..819
FT                   /note="Missing (in isoform 2)"
FT                   /id="VSP_057612"
SQ   SEQUENCE   819 AA;  89487 MW;  41BE7E6EA743AE1F CRC64;
     MDKEKDHEVE WLEAQKIEIS VDLLAAAKQH LLFLETVDRN RWLYDGPALE KAIYRYNACW
     LPLLVKYSES SSVSEGSLVP PLDCEWIWHC HRLNPVRYNS DCEQFYGRVL DNSGVLSSVD
     GNCKLKTEDL WKRLYPDEPY ELDLDNIDLE DISEKSSALE KCTKYDLVSA VKRQSPFYYQ
     VSRSHVNSDI FLQEAVARYK GFLYLIKMNR ERSLKRFCVP TYDVDLIWHT HQLHPVSYCD
     DMVKLIGKVL EHDDTDSDRG KGKKLDTGFS KTTAQWEETF GTRYWKAGAM HRGKTPVPVT
     NSPYASDVLV KDPTAKDDFQ NLIQFPEVEV VEVLLEIIGV RNLPDGHKGK VSVMFSKTQP
     DSLFNAERRL TILSEVGEKQ VATFQCEPTG ELVFKLISCS PSKIPVSREP KNLGFASLSL
     KEFLFPVITQ LSVEKWLELT PSKGSQTDTK PISLRVAVSF TPPVRSPSVL HMVQSRPSCK
     GSCFFPIIGK SRLAKSSTHI VDETQTEVIT LQIRNSADGG ILKDDQRQVM GVTDSGETRV
     LAVYTGSFWS LLDSKWSLKQ INASTADNPL FEILGPRVVK IFSGRKLDYE PKHCANLRSD
     LDFMTLVEFS KQHPYGKTVG LVDMRFGSIE AKENWLLLPG IVSAFILHTV LKKGGSEGFN
     VTTKDIKEES KQTKLVAATE NNVNANSTNV ETQTAITAPK KGSGCGGGCS GECGNMVKAA
     NASGCGSSCS GECGDMVKSA ANASGCGSGC SGECGNMVKA ANASGGGYGA RCKAAKASGC
     GGGCGGGCGG GCGDMVKSVN ASGCGGGCNG ECGNMVKAA