ID   GRDP2_ARATH             Reviewed;         787 AA.
AC   Q9SZJ2;
DT   29-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Glycine-rich domain-containing protein 2 {ECO:0000303|PubMed:25653657};
DE            Short=AtGRDP2 {ECO:0000303|PubMed:25653657};
GN   Name=GRDP2 {ECO:0000303|PubMed:25653657};
GN   OrderedLocusNames=At4g37900 {ECO:0000312|Araport:AT4G37900};
GN   ORFNames=F20D10.20 {ECO:0000312|EMBL:CAB37530.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617198; DOI=10.1038/47134;
RA   Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA   Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA   Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA   de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA   Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA   Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA   Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA   Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA   Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA   Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA   Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA   Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA   Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA   Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA   Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA   Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA   Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA   Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA   Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA   Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA   Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA   Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA   Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA   Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA   Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA   Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA   de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA   Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA   Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA   Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA   Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA   Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA   Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA   Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA   Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA   Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA   O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA   Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA   Martienssen R., McCombie W.R.;
RT   "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL   Nature 402:769-777(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   FUNCTION, DISRUPTION PHENOTYPE, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE,
RP   AND INDUCTION BY AUXIN.
RC   STRAIN=cv. Columbia;
RX   PubMed=25653657; DOI=10.3389/fpls.2014.00782;
RA   Ortega-Amaro M.A., Rodriguez-Hernandez A.A., Rodriguez-Kessler M.,
RA   Hernandez-Lucero E., Rosales-Mendoza S., Ibanez-Salazar A.,
RA   Delgado-Sanchez P., Jimenez-Bremont J.F.;
RT   "Overexpression of AtGRDP2, a novel glycine-rich domain protein,
RT   accelerates plant growth and improves stress tolerance.";
RL   Front. Plant Sci. 5:782-782(2014).
CC   -!- FUNCTION: Involved in development and stress responses, probably
CC       through an auxin-dependent mechanism. {ECO:0000269|PubMed:25653657}.
CC   -!- TISSUE SPECIFICITY: Expressed in leaves, inflorescences, buds, flowers
CC       and immature siliques. {ECO:0000269|PubMed:25653657}.
CC   -!- DEVELOPMENTAL STAGE: Develpomentally regulated, with the highest
CC       expression in flowers and immature siliques.
CC       {ECO:0000269|PubMed:25653657}.
CC   -!- INDUCTION: up-regulated upon auxin treatment.
CC       {ECO:0000269|PubMed:25653657}.
CC   -!- DISRUPTION PHENOTYPE: Delayed growth and development. Late flowering
CC       and increased sensitivity to salt stress.
CC       {ECO:0000269|PubMed:25653657}.
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DR   EMBL; AL035538; CAB37530.1; -; Genomic_DNA.
DR   EMBL; AL161592; CAB80455.1; -; Genomic_DNA.
DR   EMBL; CP002687; AEE86851.1; -; Genomic_DNA.
DR   EMBL; CP002687; ANM67181.1; -; Genomic_DNA.
DR   PIR; T05617; T05617.
DR   RefSeq; NP_001329025.1; NM_001342460.1.
DR   RefSeq; NP_195503.1; NM_119951.3.
DR   AlphaFoldDB; Q9SZJ2; -.
DR   SMR; Q9SZJ2; -.
DR   STRING; 3702.AT4G37900.1; -.
DR   PaxDb; Q9SZJ2; -.
DR   PRIDE; Q9SZJ2; -.
DR   ProteomicsDB; 222354; -.
DR   EnsemblPlants; AT4G37900.1; AT4G37900.1; AT4G37900.
DR   EnsemblPlants; AT4G37900.2; AT4G37900.2; AT4G37900.
DR   GeneID; 829946; -.
DR   Gramene; AT4G37900.1; AT4G37900.1; AT4G37900.
DR   Gramene; AT4G37900.2; AT4G37900.2; AT4G37900.
DR   KEGG; ath:AT4G37900; -.
DR   Araport; AT4G37900; -.
DR   TAIR; locus:2121013; AT4G37900.
DR   eggNOG; ENOG502QRQZ; Eukaryota.
DR   HOGENOM; CLU_011059_0_0_1; -.
DR   InParanoid; Q9SZJ2; -.
DR   OMA; MIMEGSK; -.
DR   OrthoDB; 246640at2759; -.
DR   PhylomeDB; Q9SZJ2; -.
DR   PRO; PR:Q9SZJ2; -.
DR   Proteomes; UP000006548; Chromosome 4.
DR   ExpressionAtlas; Q9SZJ2; baseline and differential.
DR   Genevisible; Q9SZJ2; AT.
DR   GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0071470; P:cellular response to osmotic stress; IMP:UniProtKB.
DR   GO; GO:0010928; P:regulation of auxin mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:2000028; P:regulation of photoperiodism, flowering; IMP:TAIR.
DR   InterPro; IPR009836; GRDP-like.
DR   PANTHER; PTHR34365; PTHR34365; 1.
DR   Pfam; PF07173; GRDP-like; 2.
PE   2: Evidence at transcript level;
KW   Auxin signaling pathway; Reference proteome; Stress response.
FT   CHAIN           1..787
FT                   /note="Glycine-rich domain-containing protein 2"
FT                   /id="PRO_0000432853"
SQ   SEQUENCE   787 AA;  86601 MW;  85A548C102D69FE4 CRC64;
     MDKEKEQTLE WNEAQKIDIS VDLLAAAKKH LLFLGAVDRN RCLYDGPALQ RAIYRYNAYW
     LPLLAQYTES SSICQGPLVP PLDCEWVWHC HRLNPVRYKT DCEQFYGRVL DNSGVVSSVN
     GNCKSQTETL WKRLYPTEPY DLDFANAISE PADVSALEKC TTYDLVLAVK RQSPFFYQVS
     RAHVDNDVFL QEAVARYKAF LYLIKGNRER SIKLFCVPTY DIDLIWHTHQ LHAISYCNDL
     TKMIGKVLEH DDTDSDRSKG KKLDTGFSGT TAQWEETFGR RYWKAGAMNR GNTPKPVTTS
     PYVCSGKKSI AKEEESQNVI QYPEVKVIEV ILEIVGVKNL PDAHKGKVFV LFSKTQPDSL
     FNAERRLTVL SESCGEKQVA LFQCEPTGEL SFQLMSSKSK SLGFTSLSFS EFLSPVTKLS
     VEKWLELTPT KRGKADDPNP ISLRVAVSFT PPTRSPTVLH LVQARPSLKG SCFLPMLRKV
     RLAKSFTRVV DETETEVINL QMRNSNDAAP KGDRRQVIGV KECGETYVLA EYDGTFWSLL
     DSKWSLKQTC NPATDGPLFE LSGTRMVKVY SGRKLEYEPK HCSKLRSEQD FMTAVEFSKQ
     HPYGKAVGLL DLKFGSIEAN EKWLVLPGMV SSFILSDLLK KEGFSAAAKD TVKANGITEE
     STEIDVLSQE KLEEETMMDV DTTTPVAVAA EKINGGARCF SKELSGNMIE EEGGHCGGCG
     GCGGCGGGGG CGGGGRCGGM TKIEGCGGGS CTGGSTGCGN CGGGCGNMMK NNANGNAPSV
     ENDAVTA