ID   GREB_HAEDU              Reviewed;         162 AA.
AC   Q7VM42;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Transcription elongation factor GreB {ECO:0000255|HAMAP-Rule:MF_00930};
DE   AltName: Full=Transcript cleavage factor GreB {ECO:0000255|HAMAP-Rule:MF_00930};
GN   Name=greB {ECO:0000255|HAMAP-Rule:MF_00930}; OrderedLocusNames=HD_1167;
OS   Haemophilus ducreyi (strain 35000HP / ATCC 700724).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=233412;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=35000HP / ATCC 700724;
RA   Munson R.S. Jr., Ray W.C., Mahairas G., Sabo P., Mungur R., Johnson L.,
RA   Nguyen D., Wang J., Forst C., Hood L.;
RT   "The complete genome sequence of Haemophilus ducreyi.";
RL   Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Necessary for efficient RNA polymerase transcription
CC       elongation past template-encoded arresting sites. The arresting sites
CC       in DNA have the property of trapping a certain fraction of elongating
CC       RNA polymerases that pass through, resulting in locked ternary
CC       complexes. Cleavage of the nascent transcript by cleavage factors such
CC       as GreA or GreB allows the resumption of elongation from the new
CC       3'terminus. GreB releases sequences of up to 9 nucleotides in length.
CC       {ECO:0000255|HAMAP-Rule:MF_00930}.
CC   -!- SIMILARITY: Belongs to the GreA/GreB family. GreB subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00930}.
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DR   EMBL; AE017143; AAP96021.1; -; Genomic_DNA.
DR   RefSeq; WP_010945070.1; NC_002940.2.
DR   AlphaFoldDB; Q7VM42; -.
DR   SMR; Q7VM42; -.
DR   STRING; 233412.HD_1167; -.
DR   EnsemblBacteria; AAP96021; AAP96021; HD_1167.
DR   KEGG; hdu:HD_1167; -.
DR   eggNOG; COG0782; Bacteria.
DR   HOGENOM; CLU_101379_3_0_6; -.
DR   OMA; DQIFFGA; -.
DR   Proteomes; UP000001022; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0070063; F:RNA polymerase binding; IEA:InterPro.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.287.180; -; 1.
DR   Gene3D; 3.10.50.30; -; 1.
DR   HAMAP; MF_00105; GreA_GreB; 1.
DR   HAMAP; MF_00930; GreB; 1.
DR   InterPro; IPR036953; GreA/GreB_C_sf.
DR   InterPro; IPR018151; TF_GreA/GreB_CS.
DR   InterPro; IPR028624; Tscrpt_elong_fac_GreA/B.
DR   InterPro; IPR001437; Tscrpt_elong_fac_GreA/B_C.
DR   InterPro; IPR023459; Tscrpt_elong_fac_GreA/B_fam.
DR   InterPro; IPR022691; Tscrpt_elong_fac_GreA/B_N.
DR   InterPro; IPR036805; Tscrpt_elong_fac_GreA/B_N_sf.
DR   InterPro; IPR006358; Tscrpt_elong_fac_GreB.
DR   PANTHER; PTHR30437; PTHR30437; 1.
DR   Pfam; PF01272; GreA_GreB; 1.
DR   Pfam; PF03449; GreA_GreB_N; 1.
DR   PIRSF; PIRSF006092; GreA_GreB; 1.
DR   SUPFAM; SSF46557; SSF46557; 1.
DR   TIGRFAMs; TIGR01461; greB; 1.
DR   PROSITE; PS00829; GREAB_1; 1.
DR   PROSITE; PS00830; GREAB_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..162
FT                   /note="Transcription elongation factor GreB"
FT                   /id="PRO_0000176929"
FT   COILED          52..76
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00930"
SQ   SEQUENCE   162 AA;  18913 MW;  DB49EBF0A4258EBF CRC64;
     MAKSNYITRA GWQALDQELK YLWKEERPKV TQSVSEAAAL GDRSENAEYI YGKRRLREID
     RRIRFLSKRL EALQIIDYHP QQAGKVFFGA WIELENNEGE INQYRIVGCD EFDPTKNWIS
     IDSPVARALI GKCVDDEIEV QTPTGKAVFY INKIWYDTKS LY