ID   GREB_VIBVU              Reviewed;         160 AA.
AC   Q8DDU7;
DT   23-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2003, sequence version 2.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Transcription elongation factor GreB {ECO:0000255|HAMAP-Rule:MF_00930};
DE   AltName: Full=Transcript cleavage factor GreB {ECO:0000255|HAMAP-Rule:MF_00930};
GN   Name=greB {ECO:0000255|HAMAP-Rule:MF_00930}; OrderedLocusNames=VV1_0859;
OS   Vibrio vulnificus (strain CMCP6).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=216895;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CMCP6;
RA   Rhee J.H., Kim S.Y., Chung S.S., Kim J.J., Moon Y.H., Jeong H., Choy H.E.;
RT   "Complete genome sequence of Vibrio vulnificus CMCP6.";
RL   Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Necessary for efficient RNA polymerase transcription
CC       elongation past template-encoded arresting sites. The arresting sites
CC       in DNA have the property of trapping a certain fraction of elongating
CC       RNA polymerases that pass through, resulting in locked ternary
CC       complexes. Cleavage of the nascent transcript by cleavage factors such
CC       as GreA or GreB allows the resumption of elongation from the new
CC       3'terminus. GreB releases sequences of up to 9 nucleotides in length.
CC       {ECO:0000255|HAMAP-Rule:MF_00930}.
CC   -!- SIMILARITY: Belongs to the GreA/GreB family. GreB subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00930}.
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DR   EMBL; AE016795; AAO09362.2; -; Genomic_DNA.
DR   RefSeq; WP_011078926.1; NC_004459.3.
DR   AlphaFoldDB; Q8DDU7; -.
DR   SMR; Q8DDU7; -.
DR   EnsemblBacteria; AAO09362; AAO09362; VV1_0859.
DR   GeneID; 66963617; -.
DR   KEGG; vvu:VV1_0859; -.
DR   HOGENOM; CLU_101379_3_0_6; -.
DR   OMA; DQIFFGA; -.
DR   Proteomes; UP000002275; Chromosome 1.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0070063; F:RNA polymerase binding; IEA:InterPro.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.287.180; -; 1.
DR   Gene3D; 3.10.50.30; -; 1.
DR   HAMAP; MF_00105; GreA_GreB; 1.
DR   HAMAP; MF_00930; GreB; 1.
DR   InterPro; IPR036953; GreA/GreB_C_sf.
DR   InterPro; IPR018151; TF_GreA/GreB_CS.
DR   InterPro; IPR028624; Tscrpt_elong_fac_GreA/B.
DR   InterPro; IPR001437; Tscrpt_elong_fac_GreA/B_C.
DR   InterPro; IPR023459; Tscrpt_elong_fac_GreA/B_fam.
DR   InterPro; IPR022691; Tscrpt_elong_fac_GreA/B_N.
DR   InterPro; IPR036805; Tscrpt_elong_fac_GreA/B_N_sf.
DR   InterPro; IPR006358; Tscrpt_elong_fac_GreB.
DR   PANTHER; PTHR30437; PTHR30437; 1.
DR   Pfam; PF01272; GreA_GreB; 1.
DR   Pfam; PF03449; GreA_GreB_N; 1.
DR   PIRSF; PIRSF006092; GreA_GreB; 1.
DR   SUPFAM; SSF46557; SSF46557; 1.
DR   TIGRFAMs; TIGR01461; greB; 1.
DR   PROSITE; PS00829; GREAB_1; 1.
DR   PROSITE; PS00830; GREAB_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..160
FT                   /note="Transcription elongation factor GreB"
FT                   /id="PRO_0000176994"
SQ   SEQUENCE   160 AA;  18712 MW;  C970A0B7F47005FB CRC64;
     MKTKMITREG YNKLKQELDY LWKEHRPEIT QKVSWAASLG DRSENADYTY NKRLLRQIDR
     RVRFLSKFLP EVKIVDYAPQ QEGKVFFGAW VEIENEAGEV MKFRIVGPEE IYGDAKGYIS
     IDSPMARALL KKEVDDEVQV PTPSGIKEWF INSIEYDKGE