ID   GRF3_ORYSJ              Reviewed;         387 AA.
AC   Q6AWY6; Q0JAG0; Q7X7T1;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2012, sequence version 2.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Growth-regulating factor 3;
DE            Short=OsGRF3;
DE   AltName: Full=Transcription activator GRF3;
GN   Name=GRF3; OrderedLocusNames=Os04g0600900, LOC_Os04g51190;
GN   ORFNames=OsJ_16036, OSJNBa0083N12.16;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12447439; DOI=10.1038/nature01183;
RA   Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA   Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA   Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA   Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA   Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA   Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA   Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA   Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA   Li J., Hong G., Xue Y., Han B.;
RT   "Sequence and analysis of rice chromosome 4.";
RL   Nature 420:316-320(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [6]
RP   IDENTIFICATION, AND GENE FAMILY.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15295073; DOI=10.1093/pcp/pch098;
RA   Choi D., Kim J.H., Kende H.;
RT   "Whole genome analysis of the OsGRF gene family encoding plant-specific
RT   putative transcription activators in rice (Oryza sativa L.).";
RL   Plant Cell Physiol. 45:897-904(2004).
CC   -!- FUNCTION: Transcription activator that plays a regulatory role in
CC       gibberellin-induced stem elongation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU01002}.
CC   -!- DOMAIN: The QLQ domain and WRC domain may be involved in protein-
CC       protein interaction and DNA-binding, respectively.
CC   -!- SIMILARITY: Belongs to the GRF family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAF15677.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=DAA05207.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AL606683; CAD41819.2; -; Genomic_DNA.
DR   EMBL; AP008210; BAF15677.2; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014960; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CM000141; EEE61616.1; -; Genomic_DNA.
DR   EMBL; BK004858; DAA05207.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_015634332.1; XM_015778846.1.
DR   RefSeq; XP_015634333.1; XM_015778847.1.
DR   AlphaFoldDB; Q6AWY6; -.
DR   STRING; 4530.OS04T0600900-01; -.
DR   PaxDb; Q6AWY6; -.
DR   PRIDE; Q6AWY6; -.
DR   GeneID; 4336879; -.
DR   KEGG; osa:4336879; -.
DR   eggNOG; ENOG502QSFK; Eukaryota.
DR   HOGENOM; CLU_037908_0_0_1; -.
DR   InParanoid; Q6AWY6; -.
DR   OrthoDB; 1097140at2759; -.
DR   Proteomes; UP000000763; Chromosome 4.
DR   Proteomes; UP000007752; Chromosome 4.
DR   Proteomes; UP000059680; Chromosome 4.
DR   Genevisible; Q6AWY6; OS.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0032502; P:developmental process; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR014978; Gln-Leu-Gln_QLQ.
DR   InterPro; IPR031137; GRF.
DR   InterPro; IPR014977; WRC_dom.
DR   PANTHER; PTHR31602; PTHR31602; 1.
DR   Pfam; PF08880; QLQ; 1.
DR   Pfam; PF08879; WRC; 1.
DR   SMART; SM00951; QLQ; 1.
DR   PROSITE; PS51666; QLQ; 1.
DR   PROSITE; PS51667; WRC; 1.
PE   3: Inferred from homology;
KW   Activator; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..387
FT                   /note="Growth-regulating factor 3"
FT                   /id="PRO_0000419304"
FT   DOMAIN          53..88
FT                   /note="QLQ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01001"
FT   DOMAIN          114..158
FT                   /note="WRC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01002"
FT   REGION          145..176
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           111..129
FT                   /note="Bipartite nuclear localization signal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01002"
FT   MOTIF           147..154
FT                   /note="Bipartite nuclear localization signal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01002"
SQ   SEQUENCE   387 AA;  41618 MW;  4B905B552FC5F328 CRC64;
     MAMPFASLSP AADHRPSFIF PFCRSSPLSA VGEEAQQHMM GARWAAAVAR PPPFTAAQYE
     ELEQQALIYK YLVAGVPVPA DLLLPIRRGL DSLASRFYHH PVLGYGSYFG KKLDPEPGRC
     RRTDGKKWRC SKEAAPDSKY CERHMHRGRN RSRKPVEAQL VAPHSQPPAT APAAAVTSTA
     FQNHSLYPAI ANGGGANGGG GGGGGGGSAP GSFALGSNTQ LHMDNAASYS TVAAGAGNKD
     FRYSAYGVRP LADEHSPLIT GAMDTSIDNS WCLLPSQTST FSVSSYPMLG NLSELDQNTI
     CSLPKVEREP LSFFGSDYVT VDSGKQENQT LRPFFDEWPK ARDSWPDLAD DNSLATFSAT
     QLSISIPMAT SDFSTTSSRS HNGIYSR