GRF6_ORYSJ
ID GRF6_ORYSJ Reviewed; 603 AA.
AC Q6AWY3; B9FBC2; Q70KS3; Q851F4;
DT 03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2012, sequence version 2.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=Growth-regulating factor 6;
DE Short=OsGRF6;
DE AltName: Full=Transcription activator GRF6;
GN Name=GRF6; OrderedLocusNames=Os03g0729500, LOC_Os03g51970;
GN ORFNames=OsJ_12442, OSJNBb0011H13.8;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 343-552.
RC STRAIN=cv. Nipponbare; TISSUE=Embryo;
RX PubMed=15078336; DOI=10.1111/j.1365-313x.2004.02037.x;
RA Ye R., Yao Q.-H., Xu Z.-H., Xue H.-W.;
RT "Development of an efficient method for the isolation of factors involved
RT in gene transcription during rice embryo development.";
RL Plant J. 38:348-357(2004).
RN [8]
RP IDENTIFICATION, AND GENE FAMILY.
RC STRAIN=cv. Nipponbare;
RX PubMed=15295073; DOI=10.1093/pcp/pch098;
RA Choi D., Kim J.H., Kende H.;
RT "Whole genome analysis of the OsGRF gene family encoding plant-specific
RT putative transcription activators in rice (Oryza sativa L.).";
RL Plant Cell Physiol. 45:897-904(2004).
CC -!- FUNCTION: Transcription activator that plays a regulatory role in
CC gibberellin-induced stem elongation. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU01002}.
CC -!- DOMAIN: The QLQ domain and WRC domain may be involved in protein-
CC protein interaction and DNA-binding, respectively.
CC -!- SIMILARITY: Belongs to the GRF family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABF98682.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAF13069.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=DAA05210.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=EEE59860.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC120983; AAO38468.1; -; Genomic_DNA.
DR EMBL; DP000009; ABF98682.1; ALT_INIT; Genomic_DNA.
DR EMBL; AP008209; BAF13069.1; ALT_INIT; Genomic_DNA.
DR EMBL; AP014959; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM000140; EEE59860.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AK073578; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; AJ575243; CAE00879.1; -; mRNA.
DR EMBL; BK004861; DAA05210.1; ALT_INIT; Genomic_DNA.
DR RefSeq; XP_015628630.1; XM_015773144.1.
DR AlphaFoldDB; Q6AWY3; -.
DR STRING; 4530.OS03T0729500-01; -.
DR PaxDb; Q6AWY3; -.
DR PRIDE; Q6AWY3; -.
DR GeneID; 4333990; -.
DR KEGG; osa:4333990; -.
DR eggNOG; ENOG502QRK7; Eukaryota.
DR HOGENOM; CLU_038207_0_0_1; -.
DR InParanoid; Q6AWY3; -.
DR OrthoDB; 740672at2759; -.
DR PlantReactome; R-OSA-9035605; Regulation of seed size.
DR PlantReactome; R-OSA-9608575; Reproductive meristem phase change.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000007752; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR Genevisible; Q6AWY3; OS.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0032502; P:developmental process; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR InterPro; IPR014978; Gln-Leu-Gln_QLQ.
DR InterPro; IPR031137; GRF.
DR InterPro; IPR014977; WRC_dom.
DR PANTHER; PTHR31602; PTHR31602; 1.
DR Pfam; PF08880; QLQ; 1.
DR Pfam; PF08879; WRC; 1.
DR SMART; SM00951; QLQ; 1.
DR PROSITE; PS51666; QLQ; 1.
DR PROSITE; PS51667; WRC; 1.
PE 2: Evidence at transcript level;
KW Activator; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..603
FT /note="Growth-regulating factor 6"
FT /id="PRO_0000419307"
FT DOMAIN 158..193
FT /note="QLQ"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01001"
FT DOMAIN 223..267
FT /note="WRC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01002"
FT REGION 34..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 561..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 228..238
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01002"
FT MOTIF 256..263
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01002"
FT COMPBIAS 37..52
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 165
FT /note="I -> V (in Ref. 6; AK073578)"
FT /evidence="ECO:0000305"
FT CONFLICT 518
FT /note="V -> G (in Ref. 7; CAE00879)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 603 AA; 62896 MW; 47CFC7583CAAE57F CRC64;
MDLGGGVGVV MAAVDGGGGG ELGGGGLLGS RLMKHGRGNA GDQEHEWRPP AKQARGGDAS
SAAAAVAAAA AVSEAVKVAA PFLLGASCSP GHGGEQMLSF SSSASSCSSG GGGAAVAAAA
AAGGAMPLYY GTPASCSGLS SVSLSSSMQG AMARVRGPFT PSQWIELEHQ ALIYKYLAAN
SPVPHSLLIP IRRSLTSPYS PAYFGSSTLG WGSFQLGYSG SADPEPGRCR RTDGKKWRCS
RDAVADQKYC ERHMNRGRHR SRKHVEGQPG HAAKAMPAAV AAAAASATQP SAPAAHSGGA
VAGLAINHQH QQMKNYAANT ANPCSLQYSR DLANKHNESE QVQDSDSLSM LTSISTRNTG
SLFPFSKQHN PFEVSNSRPD FGLVSPDSLM SSPHSSLENV NLLTSQSLNE QQSSVSLQHF
VDWPRTPAQG ALAWPDAEDM QAQRSQLSIS APMASSDLSS ASTSPIHEKL MLSPLKLSRE
YSPIGLGFAA NRDEVNQGEA NWMPMFRDSL MGGPLGEVLT KNNNMEARNC LSESLNLLND
GWDSSSGFDS SPVGVLQKTT FGSVSSSTGS SPRLENHSVY DGNSNLRDDL GSVVVNHPSI
RLV
