GRF8_ORYSJ
ID GRF8_ORYSJ Reviewed; 409 AA.
AC Q6AWY1; B7EU12; Q2R2Q3;
DT 03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 13-SEP-2004, sequence version 1.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=Growth-regulating factor 8;
DE Short=OsGRF8;
DE AltName: Full=Transcription activator GRF8;
GN Name=GRF8; OrderedLocusNames=Os11g0551900, LOC_Os11g35030;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP IDENTIFICATION (ISOFORM 1), AND GENE FAMILY.
RC STRAIN=cv. Nipponbare;
RX PubMed=15295073; DOI=10.1093/pcp/pch098;
RA Choi D., Kim J.H., Kende H.;
RT "Whole genome analysis of the OsGRF gene family encoding plant-specific
RT putative transcription activators in rice (Oryza sativa L.).";
RL Plant Cell Physiol. 45:897-904(2004).
CC -!- FUNCTION: Transcription activator that plays a regulatory role in
CC gibberellin-induced stem elongation. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU01002}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q6AWY1-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q6AWY1-2; Sequence=VSP_044147, VSP_044148;
CC -!- DOMAIN: The QLQ domain and WRC domain may be involved in protein-
CC protein interaction and DNA-binding, respectively.
CC -!- MISCELLANEOUS: [Isoform 2]: May be due to an intron retention.
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the GRF family. {ECO:0000305}.
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DR EMBL; DP000010; ABA94244.2; -; Genomic_DNA.
DR EMBL; DP000010; ABG22524.1; -; Genomic_DNA.
DR EMBL; AP008217; BAF28444.1; -; Genomic_DNA.
DR EMBL; AP014967; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK103055; BAG95859.1; -; mRNA.
DR EMBL; BK004863; DAA05212.1; -; Genomic_DNA.
DR RefSeq; XP_015615703.1; XM_015760217.1. [Q6AWY1-1]
DR AlphaFoldDB; Q6AWY1; -.
DR STRING; 4530.OS11T0551900-01; -.
DR PaxDb; Q6AWY1; -.
DR PRIDE; Q6AWY1; -.
DR GeneID; 4350711; -.
DR KEGG; osa:4350711; -.
DR eggNOG; ENOG502QRK7; Eukaryota.
DR HOGENOM; CLU_1689628_0_0_1; -.
DR InParanoid; Q6AWY1; -.
DR OrthoDB; 740672at2759; -.
DR Proteomes; UP000000763; Chromosome 11.
DR Proteomes; UP000059680; Chromosome 11.
DR Genevisible; Q6AWY1; OS.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0032502; P:developmental process; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR InterPro; IPR014978; Gln-Leu-Gln_QLQ.
DR InterPro; IPR031137; GRF.
DR InterPro; IPR014977; WRC_dom.
DR PANTHER; PTHR31602; PTHR31602; 1.
DR Pfam; PF08880; QLQ; 1.
DR Pfam; PF08879; WRC; 1.
DR SMART; SM00951; QLQ; 1.
DR PROSITE; PS51666; QLQ; 1.
DR PROSITE; PS51667; WRC; 1.
PE 2: Evidence at transcript level;
KW Activator; Alternative splicing; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..409
FT /note="Growth-regulating factor 8"
FT /id="PRO_0000419309"
FT DOMAIN 107..142
FT /note="QLQ"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01001"
FT DOMAIN 158..202
FT /note="WRC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01002"
FT REGION 1..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 221..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 163..173
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01002"
FT MOTIF 191..198
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01002"
FT COMPBIAS 51..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..242
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..138
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12869764"
FT /id="VSP_044147"
FT VAR_SEQ 139..147
FT /note="PIRRSLHPW -> MKWAFYFAP (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12869764"
FT /id="VSP_044148"
SQ SEQUENCE 409 AA; 43897 MW; 5378EC94BF719843 CRC64;
MLSSCGGHGH GNPRSLQEEH HGRCGEQQGG GGGGGQEQEQ DGFLVREARA SPPSPSSSSF
LGSTSSSCSG GGGGGQMLSF SSPNGTAGLG LSSGGSMQGV LARVRGPFTP TQWMELEHQA
LIYKHIAANV SVPSSLLLPI RRSLHPWGWG SFPPGCADVE PRRCRRTDGK KWRCSRDAVG
DQKYCERHIN RGRHRSRKHV EGRKATLTIA EPSTVIAAGV SSRGHTVARQ KQVKGSAATV
SDPFSRQSNR KFLEKQNVVD QLSPMDSFDF SSTQSSPNYD NVALSPLKLH HDHDESYIGH
GAGSSSEKGS MMYESRLTVS KETLDDGPLG EVFKRKNCQS ASTEILTEKW TENPNLHCPS
GILQMATKFN SISSGNTVNS GGTAVENLIT DNGYLTARMM NPHIVPTLL
