GRIN2_CHICK
ID GRIN2_CHICK Reviewed; 518 AA.
AC Q9PWA3;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=GRIN2-like protein;
DE AltName: Full=G protein-regulated inducer of neurite outgrowth 2-like protein;
DE AltName: Full=G(o)-alpha-interacting protein 6;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND INTERACTION WITH GNAO1.
RC TISSUE=Spinal ganglion;
RX PubMed=10419452; DOI=10.1074/jbc.274.31.21507;
RA Jordan J.D., Carey K.D., Stork P.J.S., Iyengar R.;
RT "Modulation of rap activity by direct interaction of Galpha(o) with Rap1
RT GTPase-activating protein.";
RL J. Biol. Chem. 274:21507-21510(1999).
CC -!- FUNCTION: May be involved in neurite outgrowth. {ECO:0000250}.
CC -!- SUBUNIT: May interact with GNAO1.
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DR EMBL; AF151734; AAD45945.1; -; mRNA.
DR AlphaFoldDB; Q9PWA3; -.
DR STRING; 9031.ENSGALP00000003179; -.
DR PaxDb; Q9PWA3; -.
DR VEuPathDB; HostDB:geneid_395648; -.
DR eggNOG; ENOG502SG81; Eukaryota.
DR PhylomeDB; Q9PWA3; -.
DR PRO; PR:Q9PWA3; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0031175; P:neuron projection development; IBA:GO_Central.
DR InterPro; IPR026646; GPRIN2-like/GPRIN3.
DR InterPro; IPR032745; GRIN_C.
DR PANTHER; PTHR15718; PTHR15718; 1.
DR Pfam; PF15235; GRIN_C; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..518
FT /note="GRIN2-like protein"
FT /id="PRO_0000235979"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 467..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 478..499
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 518 AA; 56859 MW; 678DC26B8FCAB258 CRC64;
MGLESVVQTM NNQSPDNNSQ SRTKTTNHFL IIEQSPASWE VGDTKMCVKS STVENVSSAC
FKHQQSMGKM DEPRAVLQRS HSDLTCSCKQ QSYVTHVETS ATDSSLSSSS SRHGPSVVRM
SFQTERYGSG IRNKENTSHY QNLVTHLPAL PIDQKVPTNT FDSGGIPHNT TVYTDPGRFH
SAVLGPHMPG NGFSNRTMLS QATGIIHGGL TYSNIPNSAF SPMAMTVHNS SAVPCNIRQD
SCMKVDATIP AYCHSLPIPS IQLVPRLVCS VSESGKEQAA PDYFHSFSTS DILTYPKLVS
SVSESGLDAK RVLKCCSIPG EQLQHAQRCT QQERASSETQ TACVAFSSQQ TTDVAMKTKD
MWTMTSANDL TKGLKPALER RDAEVQTLPT MECKSVATSP AAAAESHSHV FPEVNLEQDL
EAPKSPVREV RWDDEGMTWE VYGASVDPEV LGLAIQKHLE IQIEQFQTEP AQQTGKSDED
PLNKEPSSDK MEKKRPFRTM MHSLRYPSCC ARSSTAVE