ID   GRM2B_RAT               Reviewed;         445 AA.
AC   Q5FVG8;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=GRAM domain-containing protein 2B;
DE   AltName: Full=GRAM domain-containing protein 3;
GN   Name=Gramd2b; Synonyms=Gramd3;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Liver;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-265, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22673903; DOI=10.1038/ncomms1871;
RA   Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA   Olsen J.V.;
RT   "Quantitative maps of protein phosphorylation sites across 14 different rat
RT   organs and tissues.";
RL   Nat. Commun. 3:876-876(2012).
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DR   EMBL; BC090001; AAH90001.1; -; mRNA.
DR   RefSeq; NP_001014033.1; NM_001014011.1.
DR   AlphaFoldDB; Q5FVG8; -.
DR   SMR; Q5FVG8; -.
DR   STRING; 10116.ENSRNOP00000020570; -.
DR   iPTMnet; Q5FVG8; -.
DR   PhosphoSitePlus; Q5FVG8; -.
DR   PaxDb; Q5FVG8; -.
DR   PRIDE; Q5FVG8; -.
DR   Ensembl; ENSRNOT00000020570; ENSRNOP00000020570; ENSRNOG00000015225.
DR   GeneID; 307288; -.
DR   KEGG; rno:307288; -.
DR   UCSC; RGD:1311016; rat.
DR   CTD; 65983; -.
DR   RGD; 1311016; Gramd2b.
DR   eggNOG; KOG1032; Eukaryota.
DR   GeneTree; ENSGT00940000156980; -.
DR   InParanoid; Q5FVG8; -.
DR   OMA; DTKXYIF; -.
DR   OrthoDB; 944155at2759; -.
DR   PhylomeDB; Q5FVG8; -.
DR   PRO; PR:Q5FVG8; -.
DR   Proteomes; UP000002494; Chromosome 18.
DR   Bgee; ENSRNOG00000015225; Expressed in jejunum and 20 other tissues.
DR   ExpressionAtlas; Q5FVG8; baseline and differential.
DR   Genevisible; Q5FVG8; RN.
DR   GO; GO:0005881; C:cytoplasmic microtubule; ISS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; ISO:RGD.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR004182; GRAM.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   Pfam; PF02893; GRAM; 1.
DR   SMART; SM00568; GRAM; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Phosphoprotein; Reference proteome.
FT   CHAIN           1..445
FT                   /note="GRAM domain-containing protein 2B"
FT                   /id="PRO_0000087580"
FT   DOMAIN          123..190
FT                   /note="GRAM"
FT   REGION          1..119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          277..331
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..43
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        57..93
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        94..114
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        277..311
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96HH9"
FT   MOD_RES         238
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q6PEM6"
FT   MOD_RES         255
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q6PEM6"
FT   MOD_RES         265
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
SQ   SEQUENCE   445 AA;  49229 MW;  D00457894DAFFA4C CRC64;
     MVKKPISSSD EVFKFEIPSS PKSSAGASHS STDSPSSVFL SSEAENGVED RKRFSKSPTA
     QSPTSSVEAE SPDQKRSLGL WSKSSFDGSN LLSDKNDCKT ESKADSKTER KKSSSSSQYK
     ANMHFHKLFL DVPTEEPLRQ SFTCALQKEI LYQGKLFVSE NWICFHSKVF GKDTKISIPA
     FSVTLIKKTK TALLVPNALI IATVTDRYIF VSLLSRDSTY KLLKSICGHL ENTSVGNSPN
     PSSAENSFRA DRPSSLRLDF NDEFSDLDGV VQQRRQDLEG YSSSGSQTPE SENSRDFHVT
     ESQTVLNVTK GETKPPRTDA HGSRAPDGKA KILPAHGQSE TIGILHKMES RKCPTLRHIL
     IFYAIIVCAL IISTFYMRYR INTLEERLGS LTSIMDPHST EQTAPSSLGS QVQLNVEVLC
     QELTANIVTL EKIQNNLQKL LENGD