ID   GRP1_PSIGU              Reviewed;          55 AA.
AC   P86030;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   14-OCT-2008, sequence version 1.
DT   25-MAY-2022, entry version 13.
DE   RecName: Full=Glycine-rich antimicrobial peptide Pg-AMP {ECO:0000303|PubMed:18448201};
OS   Psidium guajava (Guava) (Psidium pyriferum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Myrteae; Pimenta group;
OC   Psidium.
OX   NCBI_TaxID=120290;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, SUBUNIT, AND MASS SPECTROMETRY.
RC   TISSUE=Seed {ECO:0000269|PubMed:18448201};
RX   PubMed=18448201; DOI=10.1016/j.peptides.2008.03.013;
RA   Pelegrini P.B., Murad A.M., Silva L.P., dos Santos R.C.P., Costa F.T.,
RA   Tagliari P.D., Bloch C. Jr., Noronha E.F., Miller R.N.G., Franco O.L.;
RT   "Identification of a novel storage glycine-rich peptide from guava (Psidium
RT   guajava) seeds with activity against Gram-negative bacteria.";
RL   Peptides 29:1271-1279(2008).
CC   -!- FUNCTION: Has antibacterial activity against the Gram-negative bacteria
CC       Klebsiella sp., Proteus sp., E.coli ATCC 8739 (MIC=72 ug/ml) and
CC       K.pneumoniae (MIC=32 ug/ml). Has no activity against the Gram-negative
CC       bacterium S.typhimurium or the Gram-positive bacterium S.aureus. Does
CC       not have antifungal activity against the human and plant pathogenic
CC       fungi F.oxysporum, A.fumigatus and R.solani.
CC       {ECO:0000269|PubMed:18448201}.
CC   -!- SUBUNIT: Monomer and homodimer. Might act by homodimer formation.
CC       {ECO:0000269|PubMed:18448201}.
CC   -!- MASS SPECTROMETRY: Mass=6184.12; Method=MALDI; Note=Monomer.;
CC       Evidence={ECO:0000269|PubMed:18448201};
CC   -!- MASS SPECTROMETRY: Mass=12368.25; Method=MALDI; Note=Homodimer.;
CC       Evidence={ECO:0000269|PubMed:18448201};
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DR   AlphaFoldDB; P86030; -.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Direct protein sequencing.
FT   PEPTIDE         1..55
FT                   /note="Glycine-rich antimicrobial peptide Pg-AMP"
FT                   /evidence="ECO:0000269|PubMed:18448201"
FT                   /id="PRO_0000352772"
FT   REGION          18..55
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   55 AA;  6029 MW;  96AB2872DE68988A CRC64;
     RESPSSRMEC YEQAERYGYG GYGGGRYGGG YGSGRGQPVG QGVERSHDDN RNQPR