ID   GRT1_SCHPO              Reviewed;         648 AA.
AC   Q9C469;
DT   20-JUN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Zinc finger protein grt1;
GN   Name=grt1; ORFNames=SPBPB8B6.04c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, SUBUNIT, AND SUBCELLULAR
RP   LOCATION.
RX   PubMed=11058086; DOI=10.1242/jcs.113.22.3989;
RA   Yamada H.Y., Matsumoto S., Matsumoto T.;
RT   "High dosage expression of a zinc finger protein, Grt1, suppresses a mutant
RT   of fission yeast slp1(+), a homolog of CDC20/p55CDC/Fizzy.";
RL   J. Cell Sci. 113:3989-3999(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: May be involved in the facilitation of anaphase progression
CC       in mitosis. {ECO:0000269|PubMed:11058086}.
CC   -!- SUBUNIT: Monomer. {ECO:0000269|PubMed:11058086}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227,
CC       ECO:0000269|PubMed:11058086}.
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DR   EMBL; AF236387; AAK11149.1; -; Genomic_DNA.
DR   EMBL; CU329671; CAD27910.1; -; Genomic_DNA.
DR   RefSeq; NP_001018765.1; NM_001020940.2.
DR   AlphaFoldDB; Q9C469; -.
DR   SMR; Q9C469; -.
DR   BioGRID; 280256; 1.
DR   STRING; 4896.SPBPB8B6.04c.1; -.
DR   PaxDb; Q9C469; -.
DR   EnsemblFungi; SPBPB8B6.04c.1; SPBPB8B6.04c.1:pep; SPBPB8B6.04c.
DR   GeneID; 3361180; -.
DR   KEGG; spo:SPBPB8B6.04c; -.
DR   PomBase; SPBPB8B6.04c; grt1.
DR   VEuPathDB; FungiDB:SPBPB8B6.04c; -.
DR   eggNOG; ENOG502RIW1; Eukaryota.
DR   HOGENOM; CLU_466213_0_0_1; -.
DR   InParanoid; Q9C469; -.
DR   OMA; ICAFFTG; -.
DR   PhylomeDB; Q9C469; -.
DR   PRO; PR:Q9C469; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; NAS:PomBase.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; ISM:PomBase.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; NAS:PomBase.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR007219; Transcription_factor_dom_fun.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF04082; Fungal_trans; 1.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00906; Fungal_trans; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   1: Evidence at protein level;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..648
FT                   /note="Zinc finger protein grt1"
FT                   /id="PRO_0000114952"
FT   DNA_BIND        13..42
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
SQ   SEQUENCE   648 AA;  74419 MW;  0E393FFF9277B80B CRC64;
     MVLSKRPVRI SKACENCRKR KVKCSGGDVC FECQKYNENC VYRQFYRKIK RLKYNNDNSK
     IDNFSNEQMN IPEFISVRNL NDDSSSIEFF GPASNISFVN QLNHYLRKAE RNGYDFLSEG
     QNDITPEEER KGLEKFGMKL MVLKDNANNF DFSLSNITTE KMNGLLIAYL ETWHIPCPIF
     KAEDLFNLSV RTWKNPSASV HDKALLYLIL SIGSAASYFD LQSNSSTLPL ARGFFNLALR
     TVPHIFTELS LDAIRIVFFM SVSAGNLGDT ALSYLYSGTA VRMSLAIGLH KCKNFSNDLS
     DKYQNIRLWV SVWQWEGYWS FCVGRPSCSR QDIPIPAVPN EAFSFSGYGE HGRFLINHEH
     MRLRVFFSSC CSKIQSEIYS TNRNLLSVLQ TVEQISKEVD KEYFSSTNHQ LIRSEIGEYC
     KTLDINSCRE WFWIRIYYLY LKLMIFRPFL IFLAYVNISK TSAPDDIIEG LKRGSDQCVQ
     EAIDISKFIV QLNRKVRMLQ PIFFICTYLE SACTVLLFYI ASNSAKIQGQ LATEIWAVLR
     DTCSFLQGSS GPYVGSVSTI AKDALESLNN ILVSKKYQDN SVNNTYFDKV MQHVLVHSPA
     FDDSSDPKFE TNRSETPTQY TLDDSANDEL MIPDLQGFWE QTLDWINN