ID   GRTP6_CAEEL             Reviewed;         330 AA.
AC   Q09445; Q7JPJ1;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   30-JUL-2004, sequence version 3.
DT   25-MAY-2022, entry version 123.
DE   RecName: Full=Growth hormone-regulated TBC protein 6;
DE   AltName: Full=TBC1 domain family member 6;
GN   Name=tbc-6; ORFNames=C04A2.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
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DR   EMBL; FO080320; CCD62842.1; -; Genomic_DNA.
DR   PIR; T15401; T15401.
DR   RefSeq; NP_001021909.1; NM_001026738.5.
DR   AlphaFoldDB; Q09445; -.
DR   SMR; Q09445; -.
DR   STRING; 6239.C04A2.1.1; -.
DR   PaxDb; Q09445; -.
DR   EnsemblMetazoa; C04A2.1.1; C04A2.1.1; WBGene00015410.
DR   EnsemblMetazoa; C04A2.1.2; C04A2.1.2; WBGene00015410.
DR   GeneID; 182185; -.
DR   KEGG; cel:CELE_C04A2.1; -.
DR   UCSC; C04A2.1.1; c. elegans.
DR   CTD; 182185; -.
DR   WormBase; C04A2.1; CE36523; WBGene00015410; tbc-6.
DR   eggNOG; KOG2058; Eukaryota.
DR   GeneTree; ENSGT00940000172413; -.
DR   HOGENOM; CLU_005350_1_0_1; -.
DR   InParanoid; Q09445; -.
DR   OMA; YVFNFYP; -.
DR   OrthoDB; 1162786at2759; -.
DR   PhylomeDB; Q09445; -.
DR   PRO; PR:Q09445; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00015410; Expressed in material anatomical entity and 5 other tissues.
DR   GO; GO:0005096; F:GTPase activator activity; IBA:GO_Central.
DR   GO; GO:0090630; P:activation of GTPase activity; IBA:GO_Central.
DR   InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR   InterPro; IPR035969; Rab-GTPase_TBC_sf.
DR   Pfam; PF00566; RabGAP-TBC; 1.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF47923; SSF47923; 2.
DR   PROSITE; PS50086; TBC_RABGAP; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..330
FT                   /note="Growth hormone-regulated TBC protein 6"
FT                   /id="PRO_0000208058"
FT   DOMAIN          78..256
FT                   /note="Rab-GAP TBC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00163"
SQ   SEQUENCE   330 AA;  38367 MW;  72849953ECFC552A CRC64;
     MYVFNFYPIP RKSINFRSDV DDLGFLRPWS PQEESGCKKQ YEAWYSSYLP IVVRRRCRWE
     KENPRRNSHL LQRFVRKGIP HTFRKELWLR SCPSRADGVW QRHEVPDEVI KQIKLDLPRT
     FPDNKFLKTE GTRKTLGRAL FAVAEHIPSV GYCQGLNFVA GVILLVVNDE SRAIDLLVHL
     VSQRQEYYGK NMIGLRRDMH VLHSLLREHC PRVVVTLEKL DVGLDMLVGK WFVCWFVESL
     PMETVLRLWD CLIYEGDEWL FRIAVALFRS NMIAISSCES IDQLMTEVQN IGTSKAALYC
     HQLILKSAAL SITNKSIEAL RADAELAIPE