ID   GRXC5_ORYSJ             Reviewed;         135 AA.
AC   Q0JDM4; A0A0N7KIZ4; B8Y1G7; Q7XVL9;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 2.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Glutaredoxin-C5;
DE   AltName: Full=Protein ROXY 1;
GN   Name=GRXC5; Synonyms=ROXY1; OrderedLocusNames=Os04g0393500, LOC_Os04g32300;
GN   ORFNames=OSJNBa0072K14.2;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=19825617; DOI=10.1093/mp/ssn078;
RA   Wang Z., Xing S., Birkenbihl R.P., Zachgo S.;
RT   "Conserved functions of Arabidopsis and rice CC-type glutaredoxins in
RT   flower development and pathogen response.";
RL   Mol. Plant 2:323-335(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12447439; DOI=10.1038/nature01183;
RA   Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA   Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA   Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA   Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA   Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA   Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA   Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA   Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA   Li J., Hong G., Xue Y., Han B.;
RT   "Sequence and analysis of rice chromosome 4.";
RL   Nature 420:316-320(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [5]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [6]
RP   GENE FAMILY.
RX   PubMed=16720602; DOI=10.1093/jxb/erl001;
RA   Rouhier N., Couturier J., Jacquot J.-P.;
RT   "Genome-wide analysis of plant glutaredoxin systems.";
RL   J. Exp. Bot. 57:1685-1696(2006).
CC   -!- FUNCTION: Has a glutathione-disulfide oxidoreductase activity in the
CC       presence of NADPH and glutathione reductase. Reduces low molecular
CC       weight disulfides and proteins (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glutaredoxin family. CC-type subfamily.
CC       {ECO:0000305}.
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DR   EMBL; FJ463033; ACL68662.1; -; mRNA.
DR   EMBL; AL606621; CAD40555.1; -; Genomic_DNA.
DR   EMBL; AP008210; BAF14563.2; -; Genomic_DNA.
DR   EMBL; AP014960; BAS88985.1; -; Genomic_DNA.
DR   RefSeq; XP_015635298.1; XM_015779812.1.
DR   AlphaFoldDB; Q0JDM4; -.
DR   SMR; Q0JDM4; -.
DR   STRING; 4530.OS04T0393500-00; -.
DR   PaxDb; Q0JDM4; -.
DR   PRIDE; Q0JDM4; -.
DR   EnsemblPlants; Os04t0393500-01; Os04t0393500-01; Os04g0393500.
DR   GeneID; 4335686; -.
DR   Gramene; Os04t0393500-01; Os04t0393500-01; Os04g0393500.
DR   KEGG; osa:4335686; -.
DR   eggNOG; KOG1752; Eukaryota.
DR   HOGENOM; CLU_026126_6_1_1; -.
DR   InParanoid; Q0JDM4; -.
DR   OMA; FSMSTCC; -.
DR   OrthoDB; 1535999at2759; -.
DR   Proteomes; UP000000763; Chromosome 4.
DR   Proteomes; UP000059680; Chromosome 4.
DR   Genevisible; Q0JDM4; OS.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0097573; F:glutathione oxidoreductase activity; IEA:InterPro.
DR   InterPro; IPR011905; GlrX-like_pln_2.
DR   InterPro; IPR002109; Glutaredoxin.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR10168; PTHR10168; 1.
DR   Pfam; PF00462; Glutaredoxin; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   TIGRFAMs; TIGR02189; GlrX-like_plant; 1.
DR   PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Disulfide bond; Electron transport; Nucleus;
KW   Redox-active center; Reference proteome; Transport.
FT   CHAIN           1..135
FT                   /note="Glutaredoxin-C5"
FT                   /id="PRO_0000269667"
FT   DOMAIN          29..134
FT                   /note="Glutaredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00686"
FT   MOTIF           132..135
FT                   /note="Responsive for interaction with TGA factors"
FT                   /evidence="ECO:0000250"
FT   DISULFID        49..52
FT                   /note="Redox-active"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   135 AA;  13915 MW;  B08663765C0171B8 CRC64;
     MQYGAAAAEQ AWYMPAAAMV VAAAAETAAE RVERLASESA VVVFSVSSCC MCHAVKRLFC
     GMGVHPAVHE LDLDPRGRDL ERALARLVGA GGAAAAAVPV VFIGGKLVGA MDRVMAAHIN
     GSLVPLLKEA GALWL