GSE1_DANRE
ID GSE1_DANRE Reviewed; 1203 AA.
AC Q1LWL6;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2006, sequence version 1.
DT 03-AUG-2022, entry version 71.
DE RecName: Full=Genetic suppressor element 1;
GN Name=gse1; ORFNames=si:dkey-265o13.4;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
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DR EMBL; BX548023; CAK10902.1; -; Genomic_DNA.
DR RefSeq; NP_001074276.1; NM_001080807.1.
DR AlphaFoldDB; Q1LWL6; -.
DR SMR; Q1LWL6; -.
DR STRING; 7955.ENSDARP00000116660; -.
DR PaxDb; Q1LWL6; -.
DR Ensembl; ENSDART00000140908; ENSDARP00000116660; ENSDARG00000062020.
DR Ensembl; ENSDART00000189074; ENSDARP00000156877; ENSDARG00000062020.
DR GeneID; 567033; -.
DR KEGG; dre:567033; -.
DR CTD; 567033; -.
DR ZFIN; ZDB-GENE-030131-9569; gse1b.
DR eggNOG; ENOG502QR0Q; Eukaryota.
DR GeneTree; ENSGT00700000104539; -.
DR HOGENOM; CLU_009387_0_0_1; -.
DR InParanoid; Q1LWL6; -.
DR OMA; CWSPRGC; -.
DR PhylomeDB; Q1LWL6; -.
DR PRO; PR:Q1LWL6; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 18.
DR Bgee; ENSDARG00000062020; Expressed in retina and 21 other tissues.
DR ExpressionAtlas; Q1LWL6; baseline.
DR InterPro; IPR022207; GSE-like.
DR InterPro; IPR042337; GSE1.
DR PANTHER; PTHR17608; PTHR17608; 1.
DR Pfam; PF12540; DUF3736; 2.
PE 4: Predicted;
KW Coiled coil; Reference proteome.
FT CHAIN 1..1203
FT /note="Genetic suppressor element 1"
FT /id="PRO_0000262926"
FT REGION 1..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 137..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 299..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 514..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 796..840
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 881..994
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1050..1108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 314..398
FT /evidence="ECO:0000255"
FT COILED 856..885
FT /evidence="ECO:0000255"
FT COILED 1150..1186
FT /evidence="ECO:0000255"
FT COMPBIAS 7..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..89
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..424
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..454
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..555
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 613..641
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 811..835
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 896..922
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 968..994
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1059..1073
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1086..1102
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1203 AA; 135829 MW; 25B89334E4AD769B CRC64;
MSHEPKSPSL GMISTATRTT ATVSPLTPSP LNGSIVPNVS PASQSAHSGF AAALRKLAKQ
AEEPRGSSIS SESSPVSSPA TNHSSPVSTP KRGPMGPVIV PPGGHSVPST PPVVTIAPTK
TVNGLWRSES RSVREVESVP HGVSRDRLSS EAASAQEKGG PTVPAHLIGN PYPFGLTPAS
VMQDSRFQPL NLPRQMPHAV PTASVPEEYL RGFRPYATAE ELRMPSLPLG LDPATAAAAA
AYYHPGYLPH PSFSHYRMDD PFCLSALRSP FYQLPAGGAL PPLHPSAVHM HLPGVRYPGD
LSHPSLSSLQ SERLSERLQM EDELRQRERE REREREKERE REAEREKERE REREREKELE
RERERERERE REKERERERE MERQKERAAR EKAAESHYLT ELHGLRGAPD DRAKPDRITS
NRPEKTKESI LTTPKPIQPG IHQSLNSTHH PVPSLSSAHG LYLGPGGAGP TSLTVATMLQ
RTEEERWLAR QRKLRQEKED RQYQVSEFRQ QVLEQHLDLG RQGEIPDMNV EGHRPVPNHH
EPSSRDRDRD RDSHPLLGAP PPLISPKHQH KDHAPPPPTT LWNPAALIET STDSRRTLHD
PPSLGHYDIS RLPLPPSKHE RHYNSEKLEE GSRKRDSLDK YPPIRPSGFS EPNTFLAELE
KSTQSFLNQQ RAPLSLSGPY GELSAGFKSS GPLKNLQGHS RLAPDTTLVY DEFLQQHRRA
VSKLDLEERR RREAREKGYY YELDDSYDES DEEEVRAHLR RVSEQPPLKL DDSTEKVEFL
EMFDLTTLAH REEMMEVKRK KRRRMLRERS PSPPTVQNKR PTPTPLLTRF TPEDMNNSPE
LEDKKRFLTI FSLNHITQQQ RRDNERVEEL LQAIKQKSVT LDTIRHNPHP LCRSPAAHSS
DQSSQSPVQS EELLNGWPLS PSPSVSIPQP SADPLSISDQ HRPLSDPPKP KDSSLPPALP
DKCRANDSLP GKSSSLLNSL RQPPFAKESS VSVNGKTKPW ENFIAEEFAQ QFHESVLQST
QKALQKSKGG ALVVLEQNHA VDSSVHYNIP ELQSTPGRSK PHPHPPSSQP NGQHCPPQPS
RQELSAEESE EEEEEDDTEE DEPSTSRWQG IEAIFEAYQE YAEEQSIERQ VLHSQCRRLE
AHHYNLSLTA EQLSHSMGEL MAQKQKLAAE RENLQAELEH FKKCLTLPQS PWSRAHFKGY
PPR
