GSG1L_XENTR
ID GSG1L_XENTR Reviewed; 322 AA.
AC A4IIV4;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2007, sequence version 1.
DT 03-AUG-2022, entry version 64.
DE RecName: Full=Germ cell-specific gene 1-like protein;
DE Short=GSG1-like protein;
GN Name=gsg1l;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: As a component of the AMPAR complex, modifies AMPA receptor
CC (AMPAR) gating. {ECO:0000250}.
CC -!- SUBUNIT: Component of the AMPAR complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}. Synapse {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GSG1 family. {ECO:0000305}.
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DR EMBL; BC136169; AAI36170.1; -; mRNA.
DR RefSeq; NP_001096452.1; NM_001102982.1.
DR RefSeq; XP_012821373.1; XM_012965919.2.
DR RefSeq; XP_012821374.1; XM_012965920.1.
DR AlphaFoldDB; A4IIV4; -.
DR SMR; A4IIV4; -.
DR PaxDb; A4IIV4; -.
DR DNASU; 100125068; -.
DR Ensembl; ENSXETT00000000253; ENSXETP00000000253; ENSXETG00000000130.
DR GeneID; 100125068; -.
DR KEGG; xtr:100125068; -.
DR CTD; 146395; -.
DR Xenbase; XB-GENE-5832503; gsg1l.
DR eggNOG; ENOG502RX91; Eukaryota.
DR HOGENOM; CLU_063057_0_0_1; -.
DR InParanoid; A4IIV4; -.
DR OMA; HGEEKCR; -.
DR OrthoDB; 957556at2759; -.
DR PhylomeDB; A4IIV4; -.
DR TreeFam; TF331388; -.
DR Proteomes; UP000008143; Chromosome 7.
DR Proteomes; UP000790000; Unplaced.
DR Bgee; ENSXETG00000000130; Expressed in mesonephros and 4 other tissues.
DR GO; GO:0070161; C:anchoring junction; IEA:UniProtKB-KW.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
DR InterPro; IPR012478; GSG-1.
DR Pfam; PF07803; GSG-1; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Membrane; Reference proteome; Synapse; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..322
FT /note="Germ cell-specific gene 1-like protein"
FT /id="PRO_0000329466"
FT TOPO_DOM 1..8
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 9..29
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 30..125
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 126..146
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 147..166
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 167..187
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 188..209
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 210..230
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 231..322
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 322 AA; 36609 MW; B1EBFD77D56DAF3B CRC64;
MELSRRNRSL LSVVLNLLAL SFSVAAFFTS YWCEGTHKVV KPPCLSAVKS KNCQALALNS
SSTGSDATDT NGTLNPNVVH YNWETGDDKY AFKYFHTGFW FSCEKHQGEE ACRSFIELSP
DSEKGVLWLS VISEFLYIIL LSLGFLLMCL EFFSSSNFID GLKINAFAAI ITVLSGLLGM
VAHMMYMTVF QVTVNLGPKD WRPQTWYYGW SFGLAWLSFT LCMSASVLTL NTYTKTILEF
KYRRRIFEKN VRECNPFLDP EMVRFLWEKY IFSVSSTVED PFNWHKGFGS PIFVDIGSIT
DLPGAVKEEE RGMDLEDDGD QC