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GSG1_HUMAN
ID   GSG1_HUMAN              Reviewed;         349 AA.
AC   Q2KHT4; Q8N4M3; Q8NBR4; Q8NBS0; Q8NBT1; Q96LP9; Q96SI6; Q9BUY4;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 2.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Germ cell-specific gene 1 protein;
GN   Name=GSG1; ORFNames=UNQ709/PRO1360;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
RX   PubMed=12975309; DOI=10.1101/gr.1293003;
RA   Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J.,
RA   Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P.,
RA   Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E., Heldens S., Huang A.,
RA   Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D.,
RA   Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L.,
RA   Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C.,
RA   Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J.,
RA   Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.;
RT   "The secreted protein discovery initiative (SPDI), a large-scale effort to
RT   identify novel human secreted and transmembrane proteins: a bioinformatics
RT   assessment.";
RL   Genome Res. 13:2265-2270(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3; 4; 5; 7 AND 8).
RC   TISSUE=Retinoblastoma, and Testis;
RX   PubMed=14702039; DOI=10.1038/ng1285;
RA   Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA   Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA   Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA   Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA   Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA   Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA   Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA   Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA   Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA   Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA   Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA   Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA   Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA   Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA   Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA   Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA   Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA   Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA   Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA   Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA   Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA   Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA   Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA   Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA   Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA   Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA   Isogai T., Sugano S.;
RT   "Complete sequencing and characterization of 21,243 full-length human
RT   cDNAs.";
RL   Nat. Genet. 36:40-45(2004).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16541075; DOI=10.1038/nature04569;
RA   Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y.,
RA   Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C.,
RA   Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C.,
RA   Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R.,
RA   Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E.,
RA   Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y.,
RA   Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G.,
RA   Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H.,
RA   Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S.,
RA   Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M.,
RA   Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H.,
RA   Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q.,
RA   Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V.,
RA   Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E.,
RA   Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K.,
RA   Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D.,
RA   Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R.,
RA   David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E.,
RA   D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N.,
RA   Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N.,
RA   Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R.,
RA   Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S.,
RA   LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H.,
RA   Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P.,
RA   Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G.,
RA   Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E.,
RA   Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S.,
RA   Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O.,
RA   Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J.,
RA   Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A.,
RA   Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M.,
RA   Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I.,
RA   Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A.,
RA   Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y.,
RA   Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A.,
RA   Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F.,
RA   Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L.,
RA   Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G.,
RA   Gibbs R.A.;
RT   "The finished DNA sequence of human chromosome 12.";
RL   Nature 440:346-351(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 4 AND 6), AND VARIANT
RP   LEU-39.
RC   TISSUE=Brain, and Eye;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May cause the redistribution of PAPOLB from the cytosol to
CC       the endoplasmic reticulum. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with PAPOLB. {ECO:0000250}.
CC   -!- INTERACTION:
CC       Q2KHT4; Q12933: TRAF2; NbExp=3; IntAct=EBI-10239244, EBI-355744;
CC       Q2KHT4-3; P53365: ARFIP2; NbExp=3; IntAct=EBI-12951679, EBI-638194;
CC       Q2KHT4-3; Q9BXU8: FTHL17; NbExp=3; IntAct=EBI-12951679, EBI-12156897;
CC       Q2KHT4-3; Q96C03-3: MIEF2; NbExp=3; IntAct=EBI-12951679, EBI-11988931;
CC       Q2KHT4-3; Q9UKF7-2: PITPNC1; NbExp=3; IntAct=EBI-12951679, EBI-14223623;
CC       Q2KHT4-3; O00560: SDCBP; NbExp=3; IntAct=EBI-12951679, EBI-727004;
CC       Q2KHT4-3; Q9H0W8: SMG9; NbExp=3; IntAct=EBI-12951679, EBI-2872322;
CC       Q2KHT4-3; Q17RD7: SYT16; NbExp=3; IntAct=EBI-12951679, EBI-10238936;
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}. Note=Colocalizes with PAPOLB
CC       in the endoplasmic reticulum. {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=8;
CC       Name=1;
CC         IsoId=Q2KHT4-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q2KHT4-2; Sequence=VSP_032997;
CC       Name=3;
CC         IsoId=Q2KHT4-3; Sequence=VSP_032993;
CC       Name=4;
CC         IsoId=Q2KHT4-4; Sequence=VSP_032993, VSP_032994;
CC       Name=5;
CC         IsoId=Q2KHT4-5; Sequence=VSP_032993, VSP_032997;
CC       Name=6;
CC         IsoId=Q2KHT4-6; Sequence=VSP_032992, VSP_032993;
CC       Name=7;
CC         IsoId=Q2KHT4-7; Sequence=VSP_032992, VSP_032995;
CC       Name=8;
CC         IsoId=Q2KHT4-8; Sequence=VSP_032993, VSP_032996;
CC   -!- SIMILARITY: Belongs to the GSG1 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH01796.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAH33854.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AY358513; AAQ88877.1; -; mRNA.
DR   EMBL; AK027894; BAB55437.1; -; mRNA.
DR   EMBL; AK058045; BAB71638.1; -; mRNA.
DR   EMBL; AK075288; BAC11524.1; -; mRNA.
DR   EMBL; AK075311; BAC11540.1; -; mRNA.
DR   EMBL; AK075322; BAC11548.1; -; mRNA.
DR   EMBL; AC023790; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC079628; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH471094; EAW96299.1; -; Genomic_DNA.
DR   EMBL; BC001796; AAH01796.1; ALT_INIT; mRNA.
DR   EMBL; BC033854; AAH33854.1; ALT_INIT; mRNA.
DR   EMBL; BC112896; AAI12897.1; -; mRNA.
DR   CCDS; CCDS44835.1; -. [Q2KHT4-3]
DR   CCDS; CCDS55806.1; -. [Q2KHT4-5]
DR   CCDS; CCDS55807.1; -. [Q2KHT4-2]
DR   CCDS; CCDS55808.1; -. [Q2KHT4-6]
DR   CCDS; CCDS8659.2; -. [Q2KHT4-4]
DR   RefSeq; NP_001074023.1; NM_001080554.2.
DR   RefSeq; NP_001193771.1; NM_001206842.1. [Q2KHT4-6]
DR   RefSeq; NP_001193772.1; NM_001206843.1. [Q2KHT4-2]
DR   RefSeq; NP_001193774.1; NM_001206845.1. [Q2KHT4-5]
DR   RefSeq; NP_112579.2; NM_031289.3. [Q2KHT4-4]
DR   AlphaFoldDB; Q2KHT4; -.
DR   SMR; Q2KHT4; -.
DR   BioGRID; 123647; 14.
DR   IntAct; Q2KHT4; 10.
DR   STRING; 9606.ENSP00000405032; -.
DR   TCDB; 8.A.16.5.1; the ca(+) channel auxiliary subunit Gama1-Gama8 (ccaGama) family.
DR   PhosphoSitePlus; Q2KHT4; -.
DR   BioMuta; GSG1; -.
DR   DMDM; 187471163; -.
DR   MassIVE; Q2KHT4; -.
DR   PeptideAtlas; Q2KHT4; -.
DR   PRIDE; Q2KHT4; -.
DR   Antibodypedia; 23587; 131 antibodies from 18 providers.
DR   DNASU; 83445; -.
DR   Ensembl; ENST00000337630.10; ENSP00000336816.6; ENSG00000111305.19. [Q2KHT4-3]
DR   Ensembl; ENST00000396302.7; ENSP00000379596.3; ENSG00000111305.19. [Q2KHT4-4]
DR   Ensembl; ENST00000432710.6; ENSP00000405032.2; ENSG00000111305.19. [Q2KHT4-6]
DR   Ensembl; ENST00000457134.6; ENSP00000398384.2; ENSG00000111305.19. [Q2KHT4-5]
DR   Ensembl; ENST00000537302.5; ENSP00000441718.1; ENSG00000111305.19. [Q2KHT4-2]
DR   GeneID; 83445; -.
DR   KEGG; hsa:83445; -.
DR   UCSC; uc001rbj.4; human. [Q2KHT4-1]
DR   CTD; 83445; -.
DR   GeneCards; GSG1; -.
DR   HGNC; HGNC:19716; GSG1.
DR   HPA; ENSG00000111305; Tissue enriched (testis).
DR   neXtProt; NX_Q2KHT4; -.
DR   OpenTargets; ENSG00000111305; -.
DR   PharmGKB; PA134868096; -.
DR   VEuPathDB; HostDB:ENSG00000111305; -.
DR   eggNOG; ENOG502QRSH; Eukaryota.
DR   GeneTree; ENSGT01050000244814; -.
DR   HOGENOM; CLU_063057_0_0_1; -.
DR   InParanoid; Q2KHT4; -.
DR   OrthoDB; 957556at2759; -.
DR   PhylomeDB; Q2KHT4; -.
DR   TreeFam; TF331388; -.
DR   PathwayCommons; Q2KHT4; -.
DR   SignaLink; Q2KHT4; -.
DR   BioGRID-ORCS; 83445; 8 hits in 1069 CRISPR screens.
DR   ChiTaRS; GSG1; human.
DR   GenomeRNAi; 83445; -.
DR   Pharos; Q2KHT4; Tdark.
DR   PRO; PR:Q2KHT4; -.
DR   Proteomes; UP000005640; Chromosome 12.
DR   RNAct; Q2KHT4; protein.
DR   Bgee; ENSG00000111305; Expressed in left testis and 110 other tissues.
DR   ExpressionAtlas; Q2KHT4; baseline and differential.
DR   Genevisible; Q2KHT4; HS.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   InterPro; IPR012478; GSG-1.
DR   Pfam; PF07803; GSG-1; 1.
PE   1: Evidence at protein level;
KW   Alternative splicing; Endoplasmic reticulum; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..349
FT                   /note="Germ cell-specific gene 1 protein"
FT                   /id="PRO_0000329461"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        189..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        233..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   VAR_SEQ         1..3
FT                   /note="MAK -> MSDPSQLTQNVCLTQE (in isoform 6 and isoform
FT                   7)"
FT                   /evidence="ECO:0000303|PubMed:14702039,
FT                   ECO:0000303|PubMed:15489334"
FT                   /id="VSP_032992"
FT   VAR_SEQ         109..131
FT                   /note="Missing (in isoform 3, isoform 4, isoform 5, isoform
FT                   6 and isoform 8)"
FT                   /evidence="ECO:0000303|PubMed:12975309,
FT                   ECO:0000303|PubMed:14702039, ECO:0000303|PubMed:15489334"
FT                   /id="VSP_032993"
FT   VAR_SEQ         148..349
FT                   /note="EILWLSLGTQITYIGLQFISFLLLLTDLLLTGNPACGLKLSAFAAVSSVLSG
FT                   LLGMVAHMMYSQVFQATVNLGPEDWRPHVWNYGWAFYMAWLSFTCCMASAVTTFNTYTR
FT                   MVLEFKCKHSKSFKENPNCLPHHHQCFPRRLSSAAPTVGPLTSYHQYHNQPIHSVSEGV
FT                   DFYSELRNKGFQRGASQELKEAVRSSVEEEQC -> GEKGLLEFATLQGPCHPTLRFGG
FT                   KRLMEKASLPSPPLGLCGKNPMVIPGNADHLHRTSIHQLPPATNRLATHWEPCLWAQTE
FT                   RLCCCFLCPVRSPGDGGPHDVFTSLPSDCQLGSRRLETTCLELWLGLLHGLALLHLLHG
FT                   VGCHHLQHVHQDGAGVQVQA (in isoform 4)"
FT                   /evidence="ECO:0000303|PubMed:12975309,
FT                   ECO:0000303|PubMed:14702039, ECO:0000303|PubMed:15489334"
FT                   /id="VSP_032994"
FT   VAR_SEQ         148..349
FT                   /note="EILWLSLGTQITYIGLQFISFLLLLTDLLLTGNPACGLKLSAFAAVSSVLSG
FT                   LLGMVAHMMYSQVFQATVNLGPEDWRPHVWNYGWAFYMAWLSFTCCMASAVTTFNTYTR
FT                   MVLEFKCKHSKSFKENPNCLPHHHQCFPRRLSSAAPTVGPLTSYHQYHNQPIHSVSEGV
FT                   DFYSELRNKGFQRGASQELKEAVRSSVEEEQC -> GEKGLLEFATLQGPCHPTLRFGG
FT                   KRLMEKASLPSPPLGLCGKNPMVIPGNADHLHRTSIHQLPPATNRLATHWEPCLWAQTE
FT                   RLCCCFLCPVRSPGDGGPHDVFTSLPSDCQLGSRRLETTCLELWLGLLHGLALLHLLHG
FT                   VGCHHLQHVHQDGAGVQVQPPPWVL (in isoform 7)"
FT                   /evidence="ECO:0000303|PubMed:14702039"
FT                   /id="VSP_032995"
FT   VAR_SEQ         148..280
FT                   /note="EILWLSLGTQITYIGLQFISFLLLLTDLLLTGNPACGLKLSAFAAVSSVLSG
FT                   LLGMVAHMMYSQVFQATVNLGPEDWRPHVWNYGWAFYMAWLSFTCCMASAVTTFNTYTR
FT                   MVLEFKCKHSKSFKENPNCLPH -> GEKGLLEFATLQGPCHPTLRFGGKRLMEKASLP
FT                   SPPLGLCGKNPMVIPGNADHLHRTSTHQLPPATNRLATHWEPCLWAQTERLCCCFLCPV
FT                   RSPGDGGPHDVFTSLPSDCQLGSRRLETTCLELWLGLLHGLALLHLLHGVGCHHLQHV
FT                   (in isoform 8)"
FT                   /evidence="ECO:0000303|PubMed:14702039"
FT                   /id="VSP_032996"
FT   VAR_SEQ         148..198
FT                   /note="Missing (in isoform 2 and isoform 5)"
FT                   /evidence="ECO:0000303|PubMed:14702039,
FT                   ECO:0000303|PubMed:15489334"
FT                   /id="VSP_032997"
FT   VARIANT         39
FT                   /note="F -> L (in dbSNP:rs2306765)"
FT                   /evidence="ECO:0000269|PubMed:15489334"
FT                   /id="VAR_042684"
FT   VARIANT         67
FT                   /note="G -> V (in dbSNP:rs11546332)"
FT                   /id="VAR_042685"
FT   CONFLICT        32
FT                   /note="S -> P (in Ref. 2; BAC11548)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        259
FT                   /note="M -> V (in Ref. 2; BAC11540)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   349 AA;  39248 MW;  72AB9D98344023B5 CRC64;
     MAKMELSKAF SGQRTLLSAI LSMLSLSFST TSLLSNYWFV GTQKVPKPLC EKGLAAKCFD
     MPVSLDGDTN TSTQEVVQYN WETGDDRFSF RSFRSGMWLS CEETVEEPAL LHPQSWKQFR
     ALRSSGTAAA KGERCRSFIE LTPPAKREIL WLSLGTQITY IGLQFISFLL LLTDLLLTGN
     PACGLKLSAF AAVSSVLSGL LGMVAHMMYS QVFQATVNLG PEDWRPHVWN YGWAFYMAWL
     SFTCCMASAV TTFNTYTRMV LEFKCKHSKS FKENPNCLPH HHQCFPRRLS SAAPTVGPLT
     SYHQYHNQPI HSVSEGVDFY SELRNKGFQR GASQELKEAV RSSVEEEQC
 
 
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