GSIB_BACSU
ID GSIB_BACSU Reviewed; 123 AA.
AC P26907;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Glucose starvation-inducible protein B;
DE AltName: Full=General stress protein B;
GN Name=gsiB; OrderedLocusNames=BSU04400;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=1378051; DOI=10.1128/jb.174.13.4361-4373.1992;
RA Mueller J.P., Bukusoglu G., Sonenshein A.L.;
RT "Transcriptional regulation of Bacillus subtilis glucose starvation-
RT inducible genes: control of gsiA by the ComP-ComA signal transduction
RT system.";
RL J. Bacteriol. 174:4361-4373(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RA Kasahara Y., Nakai S., Lee S., Sadaie Y., Ogasawara N.;
RT "A 148 kbp sequence of the region between 35 and 47 degree of the Bacillus
RT subtilis genome.";
RL Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [4]
RP PROTEIN SEQUENCE OF 2-10.
RC STRAIN=168 / IS58;
RX PubMed=8012595; DOI=10.1099/00221287-140-4-741;
RA Voelker U., Engelmann S., Maul B., Riethdorf S., Voelker A., Schmid R.,
RA Mach H., Hecker M.;
RT "Analysis of the induction of general stress proteins of Bacillus
RT subtilis.";
RL Microbiology 140:741-752(1994).
CC -!- FUNCTION: Involved in an adaptive response to nutrient deprivation
CC other than sporulation.
CC -!- INDUCTION: Glucose or phosphate starvation, and addition of decoyinine.
CC Also by heat shock, salt stress and oxidative stress.
CC -!- DOMAIN: Consists mostly of well conserved tandem repeats.
CC -!- MISCELLANEOUS: Glucose deprivation induces sporulation and several
CC other adaptive responses.
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DR EMBL; X56680; CAA40009.1; -; Genomic_DNA.
DR EMBL; AB001488; BAA19277.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB12247.1; -; Genomic_DNA.
DR PIR; S26183; S26183.
DR RefSeq; NP_388321.1; NC_000964.3.
DR RefSeq; WP_003246542.1; NZ_JNCM01000031.1.
DR AlphaFoldDB; P26907; -.
DR STRING; 224308.BSU04400; -.
DR PaxDb; P26907; -.
DR PRIDE; P26907; -.
DR EnsemblBacteria; CAB12247; CAB12247; BSU_04400.
DR GeneID; 938235; -.
DR KEGG; bsu:BSU04400; -.
DR PATRIC; fig|224308.179.peg.466; -.
DR eggNOG; COG3729; Bacteria.
DR InParanoid; P26907; -.
DR OMA; TSRNHDK; -.
DR BioCyc; BSUB:BSU04400-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR InterPro; IPR019626; Stress-induced_KGG_rpt.
DR Pfam; PF10685; KGG; 5.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Reference proteome; Repeat; Stress response.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:8012595"
FT CHAIN 2..123
FT /note="Glucose starvation-inducible protein B"
FT /id="PRO_0000083866"
FT REPEAT 13..32
FT /note="1"
FT REPEAT 33..52
FT /note="2"
FT REPEAT 53..72
FT /note="3"
FT REPEAT 73..92
FT /note="4"
FT REPEAT 93..112
FT /note="5"
FT REGION 1..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 13..120
FT /note="5 X 20 AA approximate tandem repeats"
FT COMPBIAS 1..111
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 123 AA; 13798 MW; 5559C58EDAE8288E CRC64;
MADNNKMSRE EAGRKGGETT SKNHDKEFYQ EIGQKGGEAT SKNHDKEFYQ EIGEKGGEAT
SKNHDKEFYQ EIGEKGGEAT SENHDKEFYQ EIGRKGGEAT SKNHDKEFYQ EIGSKGGNAR
NND
