ID   GSIB_SALTI              Reviewed;         512 AA.
AC   Q8Z863; Q7C8T7;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Glutathione-binding protein GsiB {ECO:0000250|UniProtKB:P75797};
DE   Flags: Precursor;
GN   Name=gsiB {ECO:0000250|UniProtKB:P75797}; OrderedLocusNames=STY0888, t2040;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Part of the ABC transporter complex GsiABCD involved in
CC       glutathione import. Binds glutathione. {ECO:0000250|UniProtKB:P75797}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (GsiA),
CC       two transmembrane proteins (GsiC and GsiD) and a solute-binding protein
CC       (GsiB). {ECO:0000250|UniProtKB:P75797}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250|UniProtKB:P75797}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 5 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL513382; CAD05295.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO69652.1; -; Genomic_DNA.
DR   RefSeq; NP_455383.1; NC_003198.1.
DR   RefSeq; WP_000191432.1; NZ_WSUR01000019.1.
DR   AlphaFoldDB; Q8Z863; -.
DR   SMR; Q8Z863; -.
DR   STRING; 220341.16502059; -.
DR   EnsemblBacteria; AAO69652; AAO69652; t2040.
DR   KEGG; stt:t2040; -.
DR   KEGG; sty:STY0888; -.
DR   PATRIC; fig|220341.7.peg.897; -.
DR   eggNOG; COG0747; Bacteria.
DR   HOGENOM; CLU_017028_7_3_6; -.
DR   OMA; KESPWVP; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:UniProt.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR030678; Peptide/Ni-bd.
DR   InterPro; IPR039424; SBP_5.
DR   InterPro; IPR000914; SBP_5_dom.
DR   PANTHER; PTHR30290; PTHR30290; 1.
DR   Pfam; PF00496; SBP_bac_5; 1.
DR   PIRSF; PIRSF002741; MppA; 1.
PE   3: Inferred from homology;
KW   Periplasm; Signal; Transport.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..512
FT                   /note="Glutathione-binding protein GsiB"
FT                   /id="PRO_0000279980"
SQ   SEQUENCE   512 AA;  56552 MW;  B4EA7FD5CD8EA26D CRC64;
     MTQFITHKWL AALGLASSIA AFPALAAKDV VVAVGSNFTT LDPYDANDTL SQAVAKSFYQ
     GLFGLDKDMK VKNVLAEGYT VSDDGLTYTI TLRQGVKFQD GADFNAAAVK ANLDRASNPD
     NHLKRYNLYK NIAKTEVVDP ATVKITLKQP FSAFINILAH PATAMISPQA LEKYGKDIGF
     HPVGTGPYQL ETWNQTDFVK VKKFAGYWQQ GLPKLDSITW RPVTDNNTRA AMLQTGEAQF
     AFPIPYEQAA LLAKNKNLEL VASPSIMQRY ISMNVTQKPF DNPKVREALN YAINRQALVK
     VAFAGYATPA TGVVPPSIAY AQSYQPWPYD PAKARELLKE AGYPDGFSTT LWSSHNHSTA
     QKVLQFTQQQ LAQIGIKARI TAMDAGQRAA EVEGKGQKES GVRMFYTGWS ASTGEADWAL
     SPLFASQNWP PTQFNTAFYS NKQVDSDLAA ALKTNDPQEK TRLYKEAQDI IWKESPWIPL
     VVEKLVSAHS KNLTGFWIMP DTGFSFDDAD LK