ID   GSKIP_DROME             Reviewed;         119 AA.
AC   Q9V8F3;
DT   09-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Protein GSKIP homolog;
GN   ORFNames=CG14505;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley;
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA   Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA   Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA   An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA   Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA   Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA   Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA   Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA   Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA   Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA   Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA   Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA   Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA   Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA   Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA   Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA   Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA   McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA   Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA   Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA   Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA   Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA   Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA   Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA   Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA   Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA   Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA   Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA   Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley;
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA   Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT   review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Berkeley;
RX   PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA   Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA   Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA   Celniker S.E.;
RT   "A Drosophila full-length cDNA resource.";
RL   Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC   -!- SIMILARITY: Belongs to the GSKIP family. {ECO:0000305}.
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DR   EMBL; AE013599; AAF57714.1; -; Genomic_DNA.
DR   EMBL; AY084100; AAL89838.1; -; mRNA.
DR   RefSeq; NP_001036558.1; NM_001043093.2.
DR   RefSeq; NP_001246404.1; NM_001259475.1.
DR   AlphaFoldDB; Q9V8F3; -.
DR   SMR; Q9V8F3; -.
DR   STRING; 7227.FBpp0110100; -.
DR   PaxDb; Q9V8F3; -.
DR   DNASU; 37098; -.
DR   EnsemblMetazoa; FBtr0110803; FBpp0110100; FBgn0034327.
DR   EnsemblMetazoa; FBtr0307186; FBpp0298015; FBgn0034327.
DR   GeneID; 37098; -.
DR   KEGG; dme:Dmel_CG14505; -.
DR   UCSC; CG14505-RB; d. melanogaster.
DR   FlyBase; FBgn0034327; CG14505.
DR   VEuPathDB; VectorBase:FBgn0034327; -.
DR   eggNOG; KOG3965; Eukaryota.
DR   GeneTree; ENSGT00390000009517; -.
DR   HOGENOM; CLU_2123566_0_0_1; -.
DR   InParanoid; Q9V8F3; -.
DR   OMA; CQDFADH; -.
DR   OrthoDB; 1508955at2759; -.
DR   PhylomeDB; Q9V8F3; -.
DR   BioGRID-ORCS; 37098; 0 hits in 1 CRISPR screen.
DR   GenomeRNAi; 37098; -.
DR   PRO; PR:Q9V8F3; -.
DR   Proteomes; UP000000803; Chromosome 2R.
DR   Bgee; FBgn0034327; Expressed in testis and 6 other tissues.
DR   ExpressionAtlas; Q9V8F3; baseline and differential.
DR   Genevisible; Q9V8F3; DM.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0019207; F:kinase regulator activity; IBA:GO_Central.
DR   GO; GO:0051018; F:protein kinase A binding; IBA:GO_Central.
DR   GO; GO:0060828; P:regulation of canonical Wnt signaling pathway; IEA:InterPro.
DR   Gene3D; 3.30.2280.10; -; 1.
DR   InterPro; IPR037395; GSKIP.
DR   InterPro; IPR007967; GSKIP_dom.
DR   InterPro; IPR023231; GSKIP_dom_sf.
DR   PANTHER; PTHR12490; PTHR12490; 1.
DR   Pfam; PF05303; DUF727; 1.
DR   SUPFAM; SSF103107; SSF103107; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..119
FT                   /note="Protein GSKIP homolog"
FT                   /id="PRO_0000220954"
SQ   SEQUENCE   119 AA;  13534 MW;  83FA23FCCCE389AA CRC64;
     MALVQSDEND FHALREAQRM VDSCQDFADH LIVAEFLPHC RGVAYINIRT LEQVIYCVQL
     SRAGYRIVSY EFDDVADEVA NCDTVYESAH QLLAGISPLY GEKYGFGREP LGKRKEKQS