GSKIP_XENTR
ID GSKIP_XENTR Reviewed; 139 AA.
AC A4IIW5;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2007, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=GSK3-beta interaction protein;
DE Short=GSKIP;
GN Name=gskip;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GSKIP family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC136180; AAI36181.1; -; mRNA.
DR RefSeq; NP_001096457.1; NM_001102987.1.
DR RefSeq; XP_012823344.1; XM_012967890.2.
DR AlphaFoldDB; A4IIW5; -.
DR SMR; A4IIW5; -.
DR STRING; 8364.ENSXETP00000030479; -.
DR PaxDb; A4IIW5; -.
DR DNASU; 100125074; -.
DR Ensembl; ENSXETT00000084862; ENSXETP00000071992; ENSXETG00000034977.
DR GeneID; 100125074; -.
DR KEGG; xtr:100125074; -.
DR CTD; 51527; -.
DR Xenbase; XB-GENE-987914; gskip.
DR eggNOG; KOG3965; Eukaryota.
DR HOGENOM; CLU_143747_0_0_1; -.
DR InParanoid; A4IIW5; -.
DR OMA; FAVTEMH; -.
DR OrthoDB; 1508955at2759; -.
DR PhylomeDB; A4IIW5; -.
DR Proteomes; UP000008143; Chromosome 8.
DR Proteomes; UP000790000; Unplaced.
DR Bgee; ENSXETG00000034977; Expressed in brain and 13 other tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0019207; F:kinase regulator activity; IBA:GO_Central.
DR GO; GO:0051018; F:protein kinase A binding; IBA:GO_Central.
DR GO; GO:0060828; P:regulation of canonical Wnt signaling pathway; IEA:InterPro.
DR GO; GO:0030111; P:regulation of Wnt signaling pathway; IBA:GO_Central.
DR Gene3D; 3.30.2280.10; -; 1.
DR InterPro; IPR037395; GSKIP.
DR InterPro; IPR007967; GSKIP_dom.
DR InterPro; IPR023231; GSKIP_dom_sf.
DR PANTHER; PTHR12490; PTHR12490; 1.
DR Pfam; PF05303; DUF727; 1.
DR SUPFAM; SSF103107; SSF103107; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Reference proteome.
FT CHAIN 1..139
FT /note="GSK3-beta interaction protein"
FT /id="PRO_0000359878"
SQ SEQUENCE 139 AA; 15515 MW; CC77E964F61B7CCC CRC64;
MEVDYNPMDL PVNTVYEDES EFRDLEGTDV KDMCLEAEAI VNDVLFAVGN MFVSKTLPCA
VDVAYINVEI KEGTRYCLEL TDAGLRVAGY AFDHLAEGLC SQYHETVYSL LDSLSPAYRE
AFGNALLQRL EALKRDGQS