ID   GSM1_ASHGO              Reviewed;         482 AA.
AC   Q754J3;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Glucose starvation modulator protein 1;
GN   Name=GSM1; OrderedLocusNames=AFR081C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Transcription factor which regulates nonfermentable carbon
CC       utilization. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
CC   -!- SIMILARITY: Belongs to the ERT1/acuK family. {ECO:0000305}.
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DR   EMBL; AE016819; AAS53452.1; -; Genomic_DNA.
DR   RefSeq; NP_985628.1; NM_210982.2.
DR   AlphaFoldDB; Q754J3; -.
DR   STRING; 284811.Q754J3; -.
DR   EnsemblFungi; AAS53452; AAS53452; AGOS_AFR081C.
DR   GeneID; 4621871; -.
DR   KEGG; ago:AGOS_AFR081C; -.
DR   eggNOG; ENOG502R2ZP; Eukaryota.
DR   HOGENOM; CLU_010748_2_2_1; -.
DR   InParanoid; Q754J3; -.
DR   OMA; CHEKHLQ; -.
DR   Proteomes; UP000000591; Chromosome VI.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009267; P:cellular response to starvation; IBA:GO_Central.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS50112; PAS; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..482
FT                   /note="Glucose starvation modulator protein 1"
FT                   /id="PRO_0000406478"
FT   DOMAIN          350..422
FT                   /note="PAS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT   DNA_BIND        20..48
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
SQ   SEQUENCE   482 AA;  54640 MW;  FA80837A1F4083E1 CRC64;
     MTKRISAEEK LNRKPISRAC VFCHEKHLQC DVGRPCQNCE KRNIGESCRD NVRKVRKTRG
     RTPRSGVMNL RRARREHEDE LAIATKSRGA GEPGSTGLPQ VPSLSTLFDA NVDPVIDEEL
     LPATYVDPLG PSDVELPTSG AESFGSVWAS SEYTKLNEIL GSPGIERPRK HVPSKYEPFA
     VPATAEHSPS PSTPIELLQD HAGLLFRNTL RRHISLDTAQ SSYQASTQDT QASTVASSVS
     CEGAQFPASE AEYTSPYSFR QLVRSPEDLY RHQNSIFPHN YRQAYLELLN ILRARFLSAQ
     DEIAREEGPK QLHSIAQSIK TYYAPIFVTL TSNLIESDLK MHELILQRTL LEYENMSKMV
     NCIPMCIWRR SGEICYVSNE FISLTGFSRR ELLMRRRFIM EFFDNHGIVD YFKLFNEYLA
     FSSKEGFSST SDGQAVFSEC NLLMANNSFL KCACIWTVKR DSFNIPMLVM GQFLPIFDMD
     HT