ID   GSM1_CANAL              Reviewed;         566 AA.
AC   Q59WB9; A0A1D8PE07;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Glucose starvation modulator protein 1;
DE   AltName: Full=Zinc finger domain-containing protein 23;
GN   Name=ZCF23; Synonyms=GSM1; OrderedLocusNames=CAALFM_C107170CA;
GN   ORFNames=CaO19.11930, CaO19.4450;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Transcription factor which regulates nonfermentable carbon
CC       utilization. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
CC   -!- SIMILARITY: Belongs to the ERT1/acuK family. {ECO:0000305}.
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DR   EMBL; CP017623; AOW26369.1; -; Genomic_DNA.
DR   RefSeq; XP_713894.1; XM_708801.1.
DR   AlphaFoldDB; Q59WB9; -.
DR   STRING; 237561.Q59WB9; -.
DR   PRIDE; Q59WB9; -.
DR   GeneID; 3644477; -.
DR   KEGG; cal:CAALFM_C107170CA; -.
DR   CGD; CAL0000175205; ZCF23.
DR   VEuPathDB; FungiDB:C1_07170C_A; -.
DR   eggNOG; ENOG502R2ZP; Eukaryota.
DR   HOGENOM; CLU_010748_2_2_1; -.
DR   InParanoid; Q59WB9; -.
DR   OrthoDB; 681770at2759; -.
DR   PRO; PR:Q59WB9; -.
DR   Proteomes; UP000000559; Chromosome 1.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009267; P:cellular response to starvation; IBA:GO_Central.
DR   CDD; cd00067; GAL4; 1.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..566
FT                   /note="Glucose starvation modulator protein 1"
FT                   /id="PRO_0000406479"
FT   DNA_BIND        20..48
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          65..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          250..270
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   566 AA;  63609 MW;  ADC95D7AB98C2808 CRC64;
     MTKKLTPQEK KNRKPAVRAC VFCHQKHLQC SNERPCKNCV KRNIAHGCQD IVRKRVKYLT
     GESVPGAVSN KQSTPRKKLK TGPVSTSVSP MDSVKSELTT PVESSNHFPP PMSSSVDALP
     TTQHSAIEIP PNDQPISDIL EVPPLFDSSH MISSEAPETN ITLTTQNLIT PDPLSFHTNT
     VSNTTTDVLN KLLNDNYETE SMLSANNSNG DHLLGMAHTS SGHLSNGQQF QSNYLNEEYM
     MLGDIILQSK QASPSPSNTS TSENNTNTLS PSSFGYISNI NFEDFNQPKR KVVQKLKDSR
     PFISLGFTAD LAPHDNNNNT DYYDDKMTNN ITGKTEEGPG NPIINYNTKF TTDYVPPSIT
     NNLYKTASDL YSKELKNFYY PLSYHALTKL LKVIFGGNDL SPEEKQEKRS KLLIILKLIA
     SYRPTFIAAH RDLIQEDLLM LEMTLQRSLL DYKKLAELNS SPTIMWRRTG EIISITEDMA
     LLLEHSSFDL LKERRFIFEL MDDNSIVDYF NLFANIAVGN LKSVIQTAIQ MKTKSSNLIK
     FTCVFTIKRD IFDIPMIVIG QFLPIV