ID   GSM1_CANAW              Reviewed;         566 AA.
AC   C4YDV1;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Glucose starvation modulator protein 1;
GN   Name=GSM1; ORFNames=CAWG_00699;
OS   Candida albicans (strain WO-1) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=294748;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WO-1;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Transcription factor which regulates nonfermentable carbon
CC       utilization. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
CC   -!- SIMILARITY: Belongs to the ERT1/acuK family. {ECO:0000305}.
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DR   EMBL; CH672346; EEQ42487.1; -; Genomic_DNA.
DR   AlphaFoldDB; C4YDV1; -.
DR   STRING; 5476.C4YDV1; -.
DR   EnsemblFungi; EEQ42487; EEQ42487; CAWG_00699.
DR   VEuPathDB; FungiDB:CAWG_00699; -.
DR   HOGENOM; CLU_010748_2_2_1; -.
DR   OMA; CHEKHLQ; -.
DR   Proteomes; UP000001429; Chromosome 1, Supercontig 1.1.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..566
FT                   /note="Glucose starvation modulator protein 1"
FT                   /id="PRO_0000406480"
FT   DNA_BIND        20..48
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          63..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          250..270
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..92
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   566 AA;  63561 MW;  3C3BD192FE0FF976 CRC64;
     MTKKLTPQEK KNRKPAVRAC VFCHQKHLQC SNERPCKNCV KRNIAHGCQD IVRKRVKYLT
     GEGVPGAVSN KQSTPRKKLK TSPVSTSVSP MDSVKSELAT PVESSNHFPP PMSSSVDALP
     TTQHSAIEIP PNDQPISDIL EVPPLFDSSH MISSEAPETN ITLTTQNLIT PDPLSFHTNT
     VSNTTTDVLN KLLNDNYETE SILSANNSNG DHLLGMAHTS SGHLSNGQQF QSNYLNEEYM
     MLGDIILQSK QASPSPSNTS TSENNTNTLS PSSFGYISNI NFEDFNQPKR KVVQKLKDSR
     PFISLGFTAD LAPHDNNNNT DYYDDKMTNN ITGKTEEGPG NPIINYNTKF TTDYVPPSIT
     NNLYKTASDL YSKELKNFYY PLSYHALTKL LKVIFGGNDL SPEEKQEKRS KLLIILKLIA
     SYRPTFIAAH RDLIQEDLLM LEMTLQRSLL DYKKLAELNS SPTIMWRRTG EIISITEDMA
     LLLEHSSFDL LKERRFIFEL MDDNSIVDYF NLFANIAVGN LKSVIQTAIQ MKTKSSNLIK
     FTCVFTIKRD IFDIPMIVIG QFLPIV