ID   GSM1_CLAL4              Reviewed;         487 AA.
AC   C4Y4V1;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Glucose starvation modulator protein 1;
GN   Name=GSM1; ORFNames=CLUG_04089;
OS   Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Metschnikowiaceae; Clavispora.
OX   NCBI_TaxID=306902;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42720;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Transcription factor which regulates nonfermentable carbon
CC       utilization. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
CC   -!- SIMILARITY: Belongs to the ERT1/acuK family. {ECO:0000305}.
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DR   EMBL; CH408079; EEQ39961.1; -; Genomic_DNA.
DR   RefSeq; XP_002616848.1; XM_002616802.1.
DR   AlphaFoldDB; C4Y4V1; -.
DR   STRING; 306902.C4Y4V1; -.
DR   EnsemblFungi; EEQ39961; EEQ39961; CLUG_04089.
DR   GeneID; 8496629; -.
DR   KEGG; clu:CLUG_04089; -.
DR   VEuPathDB; FungiDB:CLUG_04089; -.
DR   HOGENOM; CLU_010748_2_1_1; -.
DR   InParanoid; C4Y4V1; -.
DR   OMA; CHEKHLQ; -.
DR   Proteomes; UP000007703; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..487
FT                   /note="Glucose starvation modulator protein 1"
FT                   /id="PRO_0000406484"
FT   DOMAIN          348..420
FT                   /note="PAS"
FT   DNA_BIND        83..111
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          1..75
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          122..158
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..27
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        127..145
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   487 AA;  55055 MW;  E44DE16024F764F5 CRC64;
     MSIRFPEIPG TTRAPGTSLS SRGIFPTSPG VPQIPTTPNS YSALLHPHKS EAKGKHPLSF
     SSSMTKRLTP QEKKARRPTS RACVFCHSKH LQCSHSRPCQ NCIKRNLAHE CRDVVRKRAK
     YMSTTEVPAV SGESSSESGR ATGENGSEMG NPPDPQIAYL DGVFERSSIH ESLQDSPMST
     PASNFNSNFL NQEYMMLGDL ISKPSSPSLD VPMMYAENPS RPFISLGQSD ERPKSPEFNN
     FDFSSLDKAQ YVSPLVSHHI YQNVQDIYAN KVIDFDYPSS YHSLTSFLRQ RFSFTGKSLS
     DSEKAKKREN LLMILRLIAS YRPTFISTHK ALFRPFDFQF LEMSFQRCLL DYENLSRLNA
     SPTIIWRRTG EIVSMSNDLV ALLGLNISTI LSKRTFILEL MYDDESIVEY FRLFESVAVG
     NLHSTIVTRC KLIKRPSEGI ETNTSMDSDY IEFCSVWTVK RDLFDLPMMV VGQFLPVLPT
     PDGFRTY